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| Helicobacter pyloriⅠ infection and children growth retardation |
| WANG Hui1, WANG Hong1, BI Yingwei1, CHEN Gang2, HE Yajie2 |
1.Department of Pediatrics,2.Department of Nuclear Medicine
3.Department of Clinical Laboratory,General Hospital of Civil Aviation of China, Beijing 100123, China |
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Abstract Objective To investigate whether the Helicobacter pylori ( Hp)infection rate and that of HpⅠ are different between short stature and normal children and whether Hp infections are related to short stature.Methods Forty-three short stature children treated at our growth and development clinic were selected as subjects,including 23 boys and 20 girls aged 3 to 14,with an average age of (6.77±3.08).The control group consisted of children of normal height who visited our clinic for health checkups, including 29 boys and 27 girls aged 3 to 14,with an average age of (6.67±2.70) years .Their height and weight were measured,while data on birth weight, gestational age,breast feeding,parents’ height,and food preferences was collected,while serum samples were collected and stored in the -80 ℃ refrigerator before being analyzed for Hp antibody and classified.Results The HpⅠinfection rate was different between short stature and normal children. The total Hp and HpⅡinfection rates were not significantly different between the two groups. Multifactor logistic analysis of height showed that food preferences were of statistical significance.Conclusions Although the HpⅠinfection rate is different between short stature and normal children, the Hp infection rate is not associated with children’s height growth.
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Received: 02 November 2017
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| [1] |
Suerbaum S,Michetti P. Helicobacter pylori infection[J].NEngl J Med, 2002,347:1175-1186.
|
| [2] |
Xu Chun-di, Liu Wei.Further research on Helicobacter pylori infection in children [J]. J Clin Pediatr,2005,23(10):686-687.
|
| [3] |
Pacifico L,Osborn J F,Tromba V. Helicobacter pylori infection and extragastric disorders in children:a critical update[J].World J Gastroenterol, 2014,20:1379-1401.
|
| [4] |
Pacifico L,Osborn J F,Tromba V.Helicobacter pylori infection and extragastic disorders in children:a critical update[J].World J Gastroenterol, 2014,20:1379-1401.
|
| [5] |
Queiroz D M,Rocha A M,Crabtree J E.Unintended consequences of Helicobacter pylori infection in children in developing countries:iron deficiency,diarrhea,and growth retardation[J].Gut Microbes, 2013,4:494-504.
|
| [6] |
Raymond J, Bergeret M, Benhamou P H, et al. A 2-year study of Helicobacter pylori in children[J]. Clin Microbiol,1994,32: 461-463.
|
| [7] |
Luis Eduardo B,Robertino M. Impact of Helicobacter pylori infection on growth of childen:a prospective cohort study[J].J Pediatr Gastroenterol Nutr,2003,37:614-619.
|
| [8] |
Robertino M, Mera M D. Long-term effects of clearing Helicobacter pylori on growth in school-age childen[J].Pediatr infect dis J,2012,31(3):263-266.
|
| [9] |
吴 斌,陈晓冰,林 希,等.幽门螺杆菌感染儿童身高生长3年随访报告[J].中国儿童保健杂志,2008,16(3):273-274.
|
| [10] |
敬柏清,石 玲.生长迟缓儿童幽门螺杆菌感染情况调查[J].检验医学与临床,2014,11(14):1929-1930.
|
| [11] |
Bineyam T,Frikre E,Aster T,et al.Effect of Helicobacter pylori infection on growth trajectories in young Ethiopian children:a longitudinal studyation[J].Int J Infect Dis,2016,50:57-66 .
|
| [12] |
周建元, 薛 英, 许春娣.无症状幽门螺旋杆菌感染对郊区儿童生长发育影响的研究[J]. 临床儿科杂志, 2001, 19(3):160-161.
|
| [13] |
Andrey I E,Fernando S.The effect of Helicobacter pylori infection on growth velocity in young children from poor urban communities in Ecuador[J].Inter J Infect Dis,2010,14:788-791.
|
| [14] |
Thamas J E,Dale A,Bunn J E G,et al.EarlyHelicobacter pyloricolonisation:the association with growth fallering in the Gambin[J].Arch Dis Child,2004,89(12):1149-1154.
|
| [15] |
Cacciari E, MenegattiM,Salardi S, et al. Helicobacter pylori infection and cytotoxic antigen associated gene” A” status in short children[ J]. J Pediatr Endocrinol Metab,1999,12(2):197- 201.
|
| [1] |
. [J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(9): 800-801. |
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2018, Vol. 29 
