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| Diagnostic value of peripheral hs-CPR,CD11b-positive cells and CD64-positive cells in early infections among premature children |
| LI Chen, JI Jinglu, WANG Yu, WEI Jihong, LI Zhaoying, LI Shaohua,and AN Na |
| Department of Pediatrics, the Affiliated Hospital of Hebei University, Hebei Baoding 071000, China |
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Abstract Objective To compare the applicability of flow cytometry analysis indexes and the traditional indexes in early diagnosis of infected preterm children.Methods Seventy-two cases of preterm children treated in our hospital were divided into the infected group and normal group based on the diagnosis.CD11b and CD64 of these patients were detected with flow cytometry, hs-CPR with immunoassays, platelet with photochemical staining turbidimetric assay, WBC analyzed with a full-automatic hematology analyzer.Statistical analysis was conducted.Results There was no significant difference in general information between the two groups of patients (P> 0.05).CD11b, Hs-CRP and CD64 in the infected group were significantly higher than those in the normal group (t=8.88, P<0.01; t=22.62, P<0.01; t=24.79, P<0.01). The sensitivity of CD11b was 0.90, the specificity was 0.90, the positive predictive value was 0.98 and negative predictive value was 0.98.Conclusions The diagnostic value of CD11b-positive cells is higher than that of Hs-CPR and CD64-positive cells for early infections among premature children.
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Received: 06 December 2017
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2018, Vol. 29 
