Pathological analysis of liquid-based cytological diagnosis in fine needle aspiration of thyroid lesion
WANG Yuxin1, WU Weiguo2，HAN Yanhua3, and SONG Zonghai4.
1. Department of Pathology,
2. Medical Unit of First Detachment, Jilin Provincial Corps, Chinese People’s Armed Police Forces, Changchun 130052, China;
3. Department of Special Examination, Hospital of Jilin Provincial Corps, Chinese People’s Armed Police Forces, Changchun 130052, China;
4. Health Office of Logistic Department, Jilin Provincial Corps, Chinese People’s Armed Police Forces, Changchun 130052
Abstract：Objective To evaluate the liquid-based cytology in the diagnosis of thyroid diseases. Methods Two hundred cases of thyroid lesion in outpatient and inpatient departments underwent liquid-based cytological examinations to compare the quality and diagnosis of traditional manual smear preparation. Results The preserved specimens and smears made with liquid-PREP showed an increased number of valuable cells, a cleaner background, uniform distribution, less thyroid colloid in the smear and clear nuclei. The positive rate of thyroid cancer was 6.55% (15/229) in liquid-PREP and 3.93% (9/229) in traditional manual smear preparation. Conclusions Liquid-PREP improves the smear quality and positive rate of cancer in thyroid fine needle aspiration cytology and can serve as a promising diagnostic method for thyroid lesion.
