Abstract：Objective To study the pathogenesis and guide clinical treatments of sleep apnea-related hypertension by comparing the endothelial function with patients suffering from primary hypertension. Methods The differences in general data, vWF, EDD and EID between 37 patients with sleep apnea-related hypertension (OSA group) and 38 patients with primary hypertension (primary group) were observed. Results There were no significant differences in BMI, systolic blood pressure and diastolic blood pressure. There were significant differences in fasting blood glucose(P<0.05).The result of vWF in OSA group was (167.13?15.41)%, while that in primary group was (129.04?13.32)%. The result of EDD in OSA group was (4.12?0.43)%, while that in primary group was(6.89?0.54)%. Increase of vWF and decrease of EDD in OSA group were significantly different(P<0.05).There were no significant differences in EID between OSA group and primary group. Conclusions The generation and development of sleep apnea-related hypertension are closely related with endothelial dysfunction . Detection of endothelial function may guide clinical treatments of sleep apnea-related hypertension.
朱海东. 睡眠呼吸暂停相关性高血压与原发性高血压血管内皮功能的比较[J]. , 2013, 24(10): 843-845.
ZHU Haidong. . A study on endothelial function in patients with sleep apnea-related hypertension. , 2013, 24(10): 843-845.
2013, Vol. 24 
