Abstract：Objective To study the pathogenic bacteria distribution and drug resistance in burn patients with infection , hospitalized from January 2009 to December 2012, and provide scientific basis for monitoring and controlling clinical anti-infection treatment and hospital infection. Methods For separating bacteria wound secretion, venous catheter, blood, pus, and sputum samples were collected from 1165 burn patients in the burn ward. The distribution characteristics and drug resistance of pathogenic bacteria were analyzed. Results 962 pathogenic strains were detected, including 518 strains of gram negative bacilli, accounting for 53.9%, 382 strains of gram positive cocci, accounting for 39.7%, 62 strains of fungi, accounting for 6.4%.In 2009,the top four pathogen detection rates from high to low, were: Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter sp, Enterobacter cloacae and from 2010 to 2012,the pathogen detection rates from high to low were: four Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Enterobacter cloacae. Visible in burn wards of this hospital infection pathogens structure changes, including methicillin-resistant Staphylococcus aureus (MRSA) detection rate increased year by year, no resistance to vancomycin. Drug resistance of Pseudomonas aeruginosa was very prominent, showing multiple antibiotic resistance. Conclusions For burn ward infection pathogen Gram-negative bacteria infection, the dominant bacteria are Pseudomonas aeruginosa, followed by Staphylococcus aureus. Drug resistance of pathogens in a very serious problem, we should constantly monitor the strain variations of warning and resistance in the ward, and control resistant strains of nosocomial infection.
刘静,韩忠学,王俭,巩静,于兰. 某院烧伤患者感染病原菌分布及耐药性调查[J]. , 2013, 24(10): 892-894.
LIU Jing,HAN Zhongxue,WANG Jian,GONG Jing,and YU Lan.. Investigation and analysis of the distribution and drug resistance of pathogenic bacteria infection in burn patients. , 2013, 24(10): 892-894.
Ullah Y,Malik S A,Ahmed J. Antimicrobial susceptibility and ESBL prevalence in Pseudomonas aeruginosa isolated from burn patients in the North West of Pakistan[J]. Burns,2009,35(7):1020-1024.
2013, Vol. 24 
