Abstract：Objective To compare the hypoglycemic effects of Billroth Ⅰ, Billroth Ⅱ, Roux-en-y gastrointestinal reconstruction operations on type 2 diabetes mellitus. Methods The literature(1994.01-2013.10)was searched about different digestive tract reconstruction operations published on the comparison of curative effect of type 2 diabetes mellitus in CBM, CMCC,CNKI, VIP, WANFANG, MEDLINE, then screened, extracted, quality was evaluated. Meta-analysis was performed by using RevMan5.0 software. Results A total of 7 articles were selected.The total numbers of cases in 378 cases,were 74 in Billroth Ⅰ, 184 in Billroth Ⅱ, and 120 in Roux-en-y. The Results of meta-analysis were as follows: (1) The blood glucose levels in Billroth Ⅰ, Billroth Ⅱ and Roux-en-y in the third month after operation were significantly lower than those preoperation. (2) No difference in blood glucose levels between Billroth Ⅰ and Billroth Ⅱ in the third month after operation. (3) The blood glucose levels in Billroth Ⅰ were significantly higher than those of Roux-en-y in the third month after operation. (4) No difference in blood glucose levels between Billroth Ⅱ and Roux-en-y in the third month after operation. (5) Half a year after operation ,the blood glucose level of Billroth I was significantly higher than that of Billroth Ⅱ and Roux-en-y.(6) Compared with Billroth Ⅱ and Roux-en-y, no difference in blood glucose levels after half a year of the operation.(7) Comparism of preoperation and six months after Billroth I operation, showed no difference in blood glucose.(8) The blood glucose levels of Billroth Ⅱ and Roux-en-y after half a year of the operation were significantly lower than that of the preoperation.(9) For Billroth Ⅱ compared with Roux-en-y, there were no differences in diabetes treatment results. Conclusions The Billroth Ⅱ and Roux-en-y operations for the treatment of type 2 diabetes mellitus are effective.
李飞,韩承新,贾元利,郑皓,达布. 3种胃肠重建方式对2型糖尿病降糖效果的meta分析[J]. , 2014, 25(8): 803-807.
LI Fei,HAN Chengxin,JIA Yuanli,ZHENG Hao,DA Bu. Hypoglycemic effects of three types of gastrointestinal reconstruction on type 2 diabetes mellitus:a meta-analysis. , 2014, 25(8): 803-807.
Detournay B,Cros S,Charbonnel B,et al. Managing type 2 diabetes in France: the ECODIA survey [J]. Diabetes metab, 2000, 26(5):363-369.
[1]
Detournay B,Cros S,Charbonnel B,et al. Managing type 2 diabetes in France: the ECODIA survey [J]. Diabetes metab, 2000, 26(5):363-369.
[2]
Stacy A B, Ali A, Hector R T, et al. Can diabetes be surgically cured long-term metabolic effects of Bariatric Surgery in Obese Patients with Type 2 Diabetes Mellitus [J] .Ann Surg, 2013,258(4):628-637.
[2]
Stacy A B, Ali A, Hector R T, et al. Can diabetes be surgically cured long-term metabolic effects of Bariatric Surgery in Obese Patients with Type 2 Diabetes Mellitus [J] .Ann Surg, 2013,258(4):628-637.
[3]
Jadad A R, Moore R A, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? [J]. Control Clin Trials, 1996, 17(1): 1-12.
[3]
Jadad A R, Moore R A, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? [J]. Control Clin Trials, 1996, 17(1): 1-12.
American Diabetes Association. Diagnosis and classification of diabetes mellitus[J]. Diabetes Care,2007, 30(Suppl 1):S42-S47.
[11]
American Diabetes Association. Diagnosis and classification of diabetes mellitus[J]. Diabetes Care,2007, 30(Suppl 1):S42-S47.
[12]
Rubino F,Forgione A,Cummings DE,et al.The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes[J].Ann Surg,2006,244(5):741-749.
[12]
Rubino F,Forgione A,Cummings DE,et al.The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes[J].Ann Surg,2006,244(5):741-749.
[13]
Patriti A,Facchiano E,Sanna A,et al.The enteroinsular axis and the recovery from type 2diabetes after bariatric surgery[J]. Obes Surg,2004,14(9):840-848.
[13]
Patriti A,Facchiano E,Sanna A,et al.The enteroinsular axis and the recovery from type 2diabetes after bariatric surgery[J]. Obes Surg,2004,14(9):840-848.
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