Abstract:Objective To study the possibility of honor guard training-induced hemoglobinuria, occurring mechanism and influencing factors. Methods To observe the soldiers’ blood erythrocyte malondialdehyde (MDA), superoxide dismutase (SOD), and plasma total antioxidant capacity (T-AOC), blood lactate (BLA) changes before and after a routine training in the honor guard, and divide them into two groups with whether they developed naked eye “hematuria” repeatly in order to observe the change in the index of and correlation with “the naked eye hematuria”. Results The MDA before training(6.57±0.64)nmol/mg, after training (6.86±0.67) nmol/mg; SOD before training (9.61±1.08) U/mg, after training (10.46±2.12 )U/mg; T-AOC before training 5.18 (3.70-6.11) U/ml, after training (7.09-9.81) U/ml; BLA before training (21.4±5.4) mmol/L, after training (31.8±12.8) mmol/L. MDA, SOD, T-AOC, BLA after training increased compared with those before training increased, with statistical significance (P<0.05). Difference in MDA, SOD, T-AOC (P<0.05) existed with correlation hematuria before and after training. Conclusions The honor guards’ antioxidant capacity of red blood cell, is changed by usual training; it may be one of the causes of training-induced hemoglobinuria.
何宗泽,李冀军,陈凤锟. 仪仗兵训练性血红蛋白尿发病机制及其影响因素探讨[J]. 武警医学, 2014, 25(10): 1032-1034.
HE Zongze, LI Jijun, CHEN Fengkun. Clinical study on mechanism of training-induced hemoglobinuria in honor guard. Med. J. Chin. Peop. Armed Poli. Forc., 2014, 25(10): 1032-1034.
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Fulles P,Mecocci P,Fano G, et al. Specific cxidative alteration in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome[J].Free Radic Biol Med,2000,29(12):1252-1259.