Relationship between olfactory dysfunction and eosinophil counts in eosinophilic chronic sinusitis
ZHAO Songhua1, SUN Shaohui1, CHEN Na1, ZHU Qi1, CHEN Yu1, SHE Wenyu2, LIU Hui3
1. Department of Otolaryngology, Jilin Provincial Corps Hospital, Chinese People’s Armed Police Forces, Changchun 130052,China; 2.Department of Otolaryngology Head and Neak Surgery, Beijing Tongren Hospital,Capital Medical University, Beijing 100730,China; 3.Department of Otolaryngology, Jilin Provincial People’s Hospital, Changchun 130021, China
Abstract：Objective To study the relationship between olfactory dysfunction and eosinophila in eosinophilic chronic rhinosinusitis. Methods 45 patients with ECRS, 29 males and 16 females, age range 23 to 65 with average 33.7. Olfactory function was evaluated by T&T method, mucosal tissue specimens were collected at the time of surgery and eosinophil counts were used to identify histologic feature. Spearman’s rank correlation was assessed. Results The olfactory dysfunction was observed in ECRS patients with 2.3±1.9 and correlated with eosinophil counts (253±102)/HP with(r=0.68,P<0.01). Conclusions The olfactory dysfunction in ECRS is correlated with eosinophil counts in olfactory nasal mucosa.
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2015, Vol. 26 
