Abstract：Objective To investigate the correlation between tissue factor (TF) and lymphangiogenesis in colorectal cancer. Methods Operation records of resected colorectal cancer and corresponding paraffin block of resected primary tumors from 2011/1/1 to 2012/1/1 in this hospital were collected. By immunohistochemistry, the expression of TF, podoplanin in tumor tissues, and microlymphatic vessel density,were observed,and the microlymphatic vessel density between TF positive and negative expression groups. Results The microlymphatic vessel density in positive TF group(47.23±26.12). was higher than that in negative group(36.77±21.56). Conclusions There is high correlation between TF and microlymphatic vessel density in colorectal cancer.
韩承新,贾元利,黑砚,蔡晓军,武金虎. 大肠癌组织因子与淋巴管形成的关系[J]. 武警医学, 2015, 26(10): 1024-1026.
HAN Chengxin, JIA Yuanli,HEI Yan, CAI Xiaojun, and WU Jinhu. Relationship between TF and lymphangiogenesis in colorectal carcinoma. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(10): 1024-1026.
McCarter M D, Clarke J H, Harken A H, et al. Lymphangiogenesis is pivotal to the trials of a successful cancer metastasisi[J]. Surgery,2004,135(2):121-124.
2015, Vol. 26 
