Therapeutic effect of laparoscopy combined with uterine artery embolization in treatment of exogenous cesarean scar pregnancy
GU Yuchan1,4, ZHAO Rong1, TIAN Biao2, YANG Feifei3, WANG Lili4, CHEN Min4, and WANG Shuhe1
1.Department of Gynecology and Obstetrics,Beijing Military General Hospital, Beijing 100700, China; 2. Graduate School, North China University of Science and Technology,Tangshan 063000,China; 3. Department of Medicine,The People’s Hospital of Yanshan County, Cangzhou 061300, China; 4. Graduate School, Dalian Medical University, Dalian 116044, China
Abstract:Objective To analyze the application value of laparoscopy combined uterine artery embolization (UAE) for the treatment of exogenous cesarean scar pregnancy.Methods We retrospectively analyzed the clinical manifestations, diagnosis, treatment and curative effect in the 14 cases of exogenous cesarean scar pregnancy treated by laparoscopy combined with uterine artery embolization,admitted in Beijing Military General Hospital from January 2010 to July 2015.Results Of the 14 cases, 13 cases of laparoscopic treatment ended up success fully for the first time who underwent were operated UAE before the operation. The blood HCG test result 2-5 d postoperative on was 25.9-5657.0 mU/L with an average of 2094.5 mU/L, on average lower by 89.64%±11.55% compared with the preoperative HCG test Results. One patient without preoperative UAE had massive hemorrhage received emergent blood and transferred to transfusion laparotomic scar lesion resection + uterine artery embolization. All the 14 patients were cured and discharged, and none of them was re-admitted.Conclusions Laparoscopy combined with uterine artery embolization (UAE) for the treatment of exogenous CSP is intuitive,safe,effective, and preoperative application of UAE can effectively reduce the intraoperative bleeding. Intraoperative application of UAE can effectively control the bleeding.
Godin P A, Bassil S, Donnez J. An ectopic pregnancy developing in a previous caesarian section scar[J]. Fertil Steril,1997,67(2): 398-400.
[2]
Jurkovic D, Hillaby K, Woelfer B, et al. First trimester diagnosis and management of pregnancies implanted into the lower uterine caesarean section scar [J]. Ultrasound Obstet Gynecol, 2003, 21(3): 220-227.
[3]
Vial Y, Petignat P, Hohlfeld P. Pregnancy in a cesarean scar[J]. Ultrasound Obstet Gynecol, 2000, 16(6): 592-593.
Qi F, Zhou W, Wang M F, et al. Uterine artery embolization with and without local methotrexate infusion for the treatment of cesarean scar pregnancy [J]. Taiwan J Obstet Gyne, 2015, 54(4):376-380.
[7]
Cao S S, Zhu L H, Jin L,et al. Uterine artery embolization in cesarean scar pregnancy: safe and effective intervention[J]. Chin Med, 2014, 127(12): 2322-2326.
[8]
Yang H,Li S Y, Ma Z, et al. Therapeutic effects of uterine artery embolisation (UAE) and methotrexate (MTX) conservative therapy used in treatment of cesarean scar pregnancy[J]. Arch Gynecol Obstet, 2015.[Epub ahead of print]
Huang Y, Li Y F, Xi R K, et al. An application of uterine artery chemoembolization in treating cesarean scar pregnancy[J]. Int J Clin Exp Med, 2015, 8(2): 2570-2577.
[11]
Ben Nagi J, Helmy S, Ofili Y D, et al. Reproductive outcomes of women with a previous history of Caesarean scar ectopic pregnancies [J]. Hum Reprod, 2007, 22(7): 2012-2015.
[12]
Yang G, Lee D, Lee S, et al. Successful live births after surgical treatments for symptomatic cesarean scar pregnancies: report of 3 cases [J]. Gynecol Obstet Invest, 2014, 78(3): 208-212.