Efficacy of CT guided percutaneous chemoablation of intra-abdominal metastatic lymph nodes
WU Bin1, XU Dawei1, and WANG Fan2
1.Department of Radiology, Beijing Municipal Corps Hospital of Chinese People’s Armed Police Force, Beijing 100027, China; 2.Department of Medical Affairs, General Hospital of Chinese People’s Armed Police Force,Beijing100039, China
Abstract：Objective To evaluate the efficacy and the application value of CT guided percutaneous chemoablation of intra-abdominal metastatic lymph nodes.Methods Twenty-eight patients with intra-abdominal metastatic lymph nodes were treated by chemoablation under CT guidance. Among them, there were 12 cases of live cancer, 10 cases of gastric cancer, 3 cases of pancreatic cancer, and 3 cases of cohrnic cancer (amounting to 31 lesions). A 22G Chiba needle was used to puncture.The chemical ablation agent was prepared [ethanol (18 ml),lauromacrogol (2 ml),lipiodol (2 ml),lobaplatin (10 mg) and epirubicin (10 mg) in a ratio of 9∶1∶1∶3∶3 were made into a suspension]. All the patients were reexamined by contrast-enhanced CT 1, 3, 6 and 12 months thereafter to evaluate the volume reduction and necrosis of tumors and were followed up for 12 months.Results The operations on all 28 patients (31 lesions) were successful without serious complications.Pain in all patients was significantly relieved, VAS score before treatment was 6.3±1.5, a month after the treatment, VAS score was 1.3±1.2 (t=13.773, P<0.05), the volumes of tumors decreased to varying degrees compared with the preoperative ones.The maximum diameter of the lesions was (4.2±0.8) cm before operations, and the maximum diameter of the lesions was (1.7±0.5) cm 12 months after operations (t=14.755, P<0.05).Conclusions CT-guided percutaneous chemoablation of intra-abdominal metastatic lymph nodes is a safe,inexpensive,effective, less invasive and easily manipulated procedure; however, its long term efficacy and influence on the survival period of patients should be further investigated.
Adler J T, Mack E, Chen H.Equal oncologic results for laparoscopic and open resection of adrenal metastases [J]. J Surg Res, 2007,140(2):159-164.
[3]
Karanikiotis C, Tentes A A, Markakidis S, et al.Large bilateral adrenal metastases in non-small cell lung cancer [J].World J Surg Oncol, 2004, 13(2): 37-37.
Heilo A, Sigstad E, Fagerlid K H, et al. Efficacy of ultrasound-guided percutaneous ethanol injection treatment in patients with a limited number of metastatic cervical lymph nodes from papillary thyroid carcinoma [J]. J Clin Endocrinol Metab, 2011, 96(9): 2750-2755.
Liu S R, Xiao Y Y, Le Pivert P J, et al. CT-guided percutaneous chemoablation using an ethanol-ethiodol-doxorubicin emulsion for the treatment of metastatic lymph node carcinoma: a comparative study [J]. Technol Cancer Res Treat, 2013,12(2):165-172.
Liang H L,Liang H L,Mar G Y,et al. Computerized-tomography-guided percutaneous tumor ablation using acetic acid injection in an aldosterone producing tumor--a novel therapy [J]. Zhonghua Yi Xue Za Zhi, 2000, 63(11): 833-837.
[15]
Yamamoto T, Iwasaki Y, Konno H. Experimental sensory ganglionectomy by way of suicide axoplasmic transport[J]. J Neurosurg,1984,60(1):108-114.
2016, Vol. 27 
