Abstract：Objective To investigate the microbial population distribution of clinically isolated bacteria and drug resistance at our hospital between 2013 and 2015 in order to contribute to clinical experience. Methods The bacteria clinically isolated at our hospital over the past three years were collected. These bacteria were isolated and identified for drug sensitivity tests. The results were retrospectively analyzed. Results The collection rate of MRSA,ESBLs of E.coil and K.pneumoniae, and MDRP was in decline while that of MRCNS and pan-drug resistant acinetobacter baumanii was on the increase. The drug resistance rate of E.coil to ampicilin and piperacillin was the highest(＞75%), but was the lowest to imipenem and PIP. The drug resistance rate of K.pneumoniae and pneumoniae to common antimicrobial agents was the lowest(＜40%).The drug resistance rate of pneumoniae to common antimicrobial agents remained low (＜30%).The drug resistance rate of A.baumanii was high except SMI-TMP and sulbactam and cefoperazone. The drug resistance rate of MRSA was higher than that of MRCNS. The collection rate of high-level amimoglycosides resistance was low. Conclusions During the three years between 2013 and 2015, strains isolated at our hospital were mostly E.coil,K.Pneumoniae, Staphylococcus aureus and A.baumanii. The isolation and drug resistance at our hospital were different from what was reported by the Mohnarin. It’s important to collect and analyze the isolation in order to guide clinically rational use of drugs and minimize drug resistance.
2016, Vol. 27 
