Comparison of CTA and MRA in diagnosis of aneurysms and aneurysm rupture risk assessment
CUI Ximin1, SONG Zhonghai1, YU Jun1, and MENG Taojiang2
1.Department of Radiology, Jilin Provincial Corps Hospital of Chinese People’s Armed Police Force,Changchun 130051,China; 2.Medical Department of Sanya Resort of Chinese People’s Armed Police Force,Sanya 572023,China
Abstract：Objective To compare and contrast the value of CTA and MRA in the diagnosis of arterial tumor and risk assessment of aneurysm rupture in order to standardize aneurysm treatment.Methods Forty-eight patients with suspected intracranial aneurysms treated in our hospital between July 2015 and August 2016 were randomly and equally divided into two groups. Group Ⅰ underwent CTA+DSA examination while group Ⅱ patients underwent MRA+DSA examination. The diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accuracy of CTA and MRA for intracranial aneurysms were compared. The value of CTA and MRA in the diagnosis of aneurysm of 5 mm was also compared.Results The diagnostic sensitivity, specificity, positive predictive value, negative predictive value, negative predictive value and accuracy of MRI in the diagnosis of intracranial tumors were slightly lower than those of CTA, but the difference was not significant between the two groups. CTA and CE-MRA were almost equally accurate in the diagnosis of aneurysms above 5 mm, but compared with 3D TOF-MRA, the diagnostic sensitivity and specificity, positive predictive value, negative predictive value,and accuracy of CTA and CE-MRA were significantly higher. The difference was of statistical significance (P<0.05).Conclusions CTA and MRA can be used as the primary means to diagnose aneurysms and assess the risk of aneurysm rupture, but the accuracy and 3D shape of CTA are better than those of MRA.
崔喜民, 宋忠海, 喻骏, 孟涛疆. CTA与MRA诊断动脉瘤及评估动脉瘤破裂风险的比较[J]. 武警医学, 2016, 27(12): 1214-1217.
CUI Ximin, SONG Zhonghai, YU Jun, and MENG Taojiang. Comparison of CTA and MRA in diagnosis of aneurysms and aneurysm rupture risk assessment. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(12): 1214-1217.
Moftakhar R1,Aagaard-Kienitz B,Johnson K,et al.Noninvasive measurement of intra-aneurysmal pressure and flow pattern using phase contrast with vastly undersampled isotropic projection imaging[J]. Radiology,2007,28(9):1710-1714.
[3]
Veysel Akgun, Bilal Battal, Yalcin Bozkurt,et al. Normal Anatomical Features and Variations of the Vertebrobasilar Circulation and Its Branches: An Analysis with 64-Detector Row CT and 3T MR Angiographies[J]. Scientific World Journal,2013,2013(1):675-677.
Cheng B, Cai W, Sun C, Kang Y, et al.3D bone subtraction CT angiography for the evaluation of intracranial aneurysms: a comparison study with 2D bone subtraction CT angiography and conventional non-subtracted CT angiography[J]. Radiol Oncol,2015,56(9):1127-1134.
Vijay Yanamadala, Sameer A. Sheth, Brian P. Walcott,et al. Non-contrast 3D time-of-flight magnetic resonance angiography for visualization of intracranial aneurysms in patients with absolute contraindications to CT or MRI contrast [J]. J Clin Neurosci,2013,20(8): 1122-1126.
[16]
TIAN-YING FENG, XUE-FENG HAN, RUI LANG,et al. Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis [J]. Exp Ther Med,2016,11(5):1930-1936.
[17]
Jia Lu, Shouhua Hu, Madhavan L,et al. A shell-based inverse approach of stress analysis in intracranial aneurysms [J]. Ann Biomed Eng,2013,41(7): 1505-1515.
[18]
Ren Y, Chen GZ, Liu Z,et al.Reproducibility of image-based computational models of intracranial aneurysm: a comparison between 3D rotational angiography, CT angiography and MR angiography[J]. Biomed Eng Online,2016 ,15(1):163-164.
[19]
Brad Seibert, Ramachandra P. Tummala,et al. Intracranial Aneurysms: Review of Current Treatment Options and Outcomes [J]. Front Neurol, 2011,2.
2016, Vol. 27 
