Abstract:Objective To evaluate the clinical applicability of artificial pleural effusion to ultrasound-guided percutaneous microwave ablation for liver cancers in the hepatic dome.Methods The clinical data of 115 patients with liver cancers in the hepatic dome collected between January 2011 and December 2013 were retrospectively analyzed, whose hepatic tumors were treated with percutaneous microwave ablation under ultrasound guidance assisted by artificial pleural effusion. The parameters related to feasibility, efficacy and safety of the procedure were assessed.Results Artificial pleural effusion was dripped into the thoracic cavity in 112 out of the 115 patients and the success rate of the procedure was 97.4%. The effective rate of the procedure was 98.2%, as ultrasound-guided liver tumor ablation was completed in 110 out of the 112 patients into whom artificial pleural effusion had been dripped into. The volume of instilled saline ranged from 500 to 1500 ml (the mean volume 962.9±219.4 ml). No major complications related to artificial pleural effusion occurred during the peri-ablation and minor complications included pain and cough.Conclusions Artificial pleural effusion can be a feasible, effective and safe procedure that can help extend the range of indications in assisting microwave ablation treatment for liver cancers in the hepatic dome under ultrasound guidance.
Hansen P D, Cassera M A, Wolf R F. Ablative technologies for hepatocellular, cholangiocarcinoma, and metastatic colorectal cancer of the liver [J].Surg Oncol Clin N Am, 2015,24(1): 97-119.
[2]
Ahmed M, Brace C L, Lee F T, et al. Principles of and advances in percutaneous ablation [J].Radiology, 2011,258(2):351-369.
Liang P, Yu J, Lu M D, et al. Practice guidelines for ultrasound-guided percutaneous microwave ablation for hepatic malignancy [J].World J Gastroenterol, 2013, 19(33): 5430-5438.
[5]
Kondo Y, Yoshida H, Tateishi R, et al. Percutaneous radiofrequency ablation of liver cancer in the hepatic dome using the intrapleural fluid infusion technique [J].Br J Surg, 2008, 95(8): 996-1004.
[6]
Wang G, Sun Y, Cong L, et al. Artificial pleural effusion in percutaneous microwave ablation of hepatic tumors near the diaphragm under the guidance of ultrasound [J].Int J Clin Exp Med,2015, 8(9): 16765-16771.
[7]
Zhuang X, Wang Q, Wang N, et al. Effects of combining transarterial chemoembolization with percutaneous microwave coagulation therapy for hepatocellular carcinoma abutting the diaphragm [J].Minim Invasive Ther Allied Technol, 2016,25(2): 107-112.
Rhim H, Lim H K. Radiofrequency ablation for hepatocellular carcinoma abutting the diaphragm: the value of artificial ascites [J].Abdominal imaging, 2009, 34(3): 371-380.
[10]
Song I, Rhim H, Lim H K, et al. Percutaneous radiofrequency ablation of hepatocellular carcinoma abutting the diaphragm and gastrointestinal tracts with the use of artificial ascites: safety and technical efficacy in 143 patients [J].Eur Radiol, 2009, 19(11): 2630-2640.
[11]
Kitchin D, Lubner M, Ziemlewicz T, et al. Microwave ablation of malignant hepatic tumours: Intraperitoneal fluid instillation prevents collateral damage and allows more aggressive case selection [J].Int J Hyperthermia, 2014, 30(5): 299-305.
[12]
Zhang D, Liang P, Yu X, et al. The value of artificial pleural effusion for percutaneous microwave ablation of liver tumour in the hepatic dome: a retrospective case-control study [J].Int J Hyperthermia, 2013, 29(7): 663-670.
[13]
Ahmed M, Solbiati L, Brace C L, et al. Image-guided tumor ablation: standardization of terminology and reporting criteria--a 10-year update[J].Radiology,2014,273(1): 241-260.