血小板参数对年轻男性STEMI患者发病的预测作用

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摘要目的评估血小板计数(platelet count,PC)、血小板平均体积(mean platelet volume,MPV)在年轻男性ST段抬高性心肌梗死(ST elevation myocardial infarction,STEMI)患者中的预测作用。方法回顾性分析了某院2015-01至2016-01收治的年轻男性STEMI患者(年龄≤45岁)42例(STEMI组),以及对照组无ACS年轻男性49例(对照组)。结果 STEMI组患者MPV明显高于对照组患者[(9.60±0.61)fl vs (9.32±0.50)fl,差异有统计学意义(P=0.033)]。经多变量logistic分析发现,MPV升高是年轻男性STEMI患者独立预测因子 (P<0.01)。结论 MPV升高是年轻男性STEMI患者独立预测因子,尤其在心血管高风险中的预测。

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	辛慧慧
	李屹
	白睿
	魏玉杰
	金至赓
	刘惠亮

关键词 ： STEMI, 年轻男性, 血小板平均体积, 血小板计数

Abstract：Objective To assess the predictive role of platelet count(PC) and mean platelet volume(MPV)in young male patients with STEMI(ST elevated myocardial infarcytion).Methods Medical data on 42 male STEMI patients under 45 years old (group A) and on another 49 patients under 45 without ACS(group B)treated in our hospital between January 2015 and January 2016 was retrospectively studied and compared.Results Patients in group A had a significantly higher mean MPV than those in group B[(9.60±0.61)(fl) vs (9.32±0.50)(fl),P=0.033].Multivariate analysis indicated that an increased MPV was an independent predictor of AMI in young male patients(P<0.001).Conclusions An incresed MPV is an independent predictive factor in young male STEMI patients.

Key words： ST elevation myocardial infarction young male mean platelet volume platelet count

收稿日期: 2017-09-05

ZTFLH:

R587.1

通讯作者: 刘惠亮,E-mail:lhl518@vip.sina.com

作者简介: 辛慧慧,硕士,医师。

引用本文:

辛慧慧, 李屹, 白睿, 魏玉杰, 金至赓, 刘惠亮. 血小板参数对年轻男性STEMI患者发病的预测作用[J]. 武警医学, 2018, 29(1): 5-6. XIN Huihui, LI Yi, BAI Rui, WEI Yujie, JIN Zhigeng, and LIU Huiliang. Predictive roles of platelet parameters in young male patients with STEMI. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(1): 5-6.

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http://journal08.magtechjournal.com/Jwk_wjyx/CN/ 或 http://journal08.magtechjournal.com/Jwk_wjyx/CN/Y2018/V29/I1/5

[1]	郑昕,李建军,杨跃进,等.近15年间急性心肌梗死患者的性别年龄演变趋势[J] .中国循环杂志,2010,25(6):441-444.
[2]	韩良富,卞小洁,陆士奇,等.血小板参数在急性心肌梗死临床评估中的作用[J] .中国急诊医学杂志,2016,25(3):349-355.
[3]	Klovaite J, Benn M, Yazdanyar S, et al . High platelet volume and increased risk of myocardial infrction:39,531 participants from the general population[J] .J Thromb Haemost,2011,9(1):49-56.
[4]	Davì G, Patrono C. Platelet activation and atherothrombosis[J] .N Engl J Med,2008,357(24):2482-2494.
[5]	Thon J N，Italiano J E. Does size matter in platelet production[J] .Blood，2012,120(8):1552-1561.
[6]	Von H P,Schmitt M M.Platelets and their chemokiness in atheroscler osis-clinical applications[J] .Front Physiol,2014,5:294
[7]	Lippi G,Filippozzi L,Salvagno G L, et al .Increased Mean Platelet Volume in Patients With Acute Coronary Syndromes [J] .Arch Pathol Lab Med,2009,133(9):1441-1443.
[8]	Endler G,Klimesch A,Sunder P H, et al .Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease[J] .Br J Haematol,2003,120(1):169-170.
[9]	Leader A, Pereg D, Lishner M. Are platelet volume indices of clinical use. A multidisciplinary review[J] .Ann Med,2012,44(8):805-816.
[10]	Chu S G,Becker R C,Berger P B.Mean platelet volume as a predictor of cardiovascul-ar risk:a systematic review and meta-analysis[J] .J Thromb Haemost,2010,8(1):148-156.
[11]	Khode V,Sindhur J,Kanbur D, et al . Mean platelet volume and other platelet volume indices in patients with stable coronary artery diseaseand acute myocardial infarction:A casecontrol study[J] .J Cardiovasc Dis Res,2012,3(4):272-275.
[12]	Gasparyan A Y,Ayvazyan L,Mikhailidis D P, et al . Mean platelet volume:a link between thrombosis and inflammation?[J] .Curr Pharm Des,2011,17（1）：47-58.
[13]	Kilicli C N,Demirtunc R,Konuralp C, et al .Could mean platelet volume be a predictive marker for acute myocardial infarction?[J] . Med Sci Monit,2005,11(8):387-392.
[14]	Greisenegger S, Endler G,Hsieh K, et al .Is elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events?[J] .Stroke,2004,35(7):1688-1691.