Abstract：Objective To analyze the MRI features of acute Marchiafava-Bignami disease(MBD)and improve the literacy and diagnosis of this disease.Methods The MRI images and clinical data of 31 cases of Marchiafava-Bignami disease proved by clinical data between January 2016 and May 2017 were retrospectively analyzed.Results Acute primary Marchiafava-Bignami disease was more common in the splenium of the corpus callosum (13/31, 41.9%). MRI showed changes in T1 and T2 signals of equal length. DWI showed high signals and slightly high signals. Twenty cases showed brain parenchymal lesions outside the corpus callosum, which were more common in semi-oval centers (20/31, 64.5%) and fronto-parietal white matter (18/31, 58.1%).Conclusions MRI can clearly show the corpus callosum and other lesions. The imaging features are specific to some extent. MRI is of great value for the early diagnosis, treatment and prognosis of this disease, which can be used as the first choice for clinical examination.
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2018, Vol. 29 
