Effect of short-term exercise interventions on preoperative blood glucose in patients with type 2 diabetes mellitus: a pilot study
GAO Xueyan1,2, GAO Hongkai2, GAO Yanhong3
1.Graduate School, Jinzhou Medical University, Jinzhou 121001,China; 2.Department of General Surgery, the Third Medical Center of PLA General Hospital, Beijing 100039, China
Abstract:Objective To tentatively investigate the effect of short-term exercise interventions on preoperative blood glucose in patients with type 2 diabetes mellitus (T2DM).Methods Forty-five patients with T2DM scheduled for surgery were randomly divided into the moderate-intensity intermittent exercise group, low-intensity continuous exercise group and control group, with fifteen cases in each. The two exercise groups were subjected to 3-5 days of exercise interventions of different intensities and in different modes. Under the same conditions, the control group received nothing more than preoperative basic care and routine education. In order to observe the effect of short-term glycemic control,the biochemical examination and the 24-hour continuous glucose monitoring system (CGMS) were used to evaluate the levels of FPG, PPG, Fins, HOMA-IR and lnIS of each subject before and after the intervention.Results (1) After three days of exercise intervention, the overall glycemic compliance rate of the moderate-intensity exercise group was higher than that of the control group (P<0.05). Except for FPG, all the other glycemic indexes were lower than those of the control group (P<0.05). The effect of exercise on PPG improvement in patients of the moderate intermittent exercise group was even more significant than in the low-intensity continuous exercise group (P<0.05). (2) Five days after the exercise intervention program, the levels of PPG were lower in the low-intensity continuous exercise group than that in the control group (P<0.05). With the exception of FPG, all the other glycemic indexes were more significantly improved in the moderate intermittent exercise group than that in the control group(P<0.05).Conclusion The short-term exercise intervention program has a positive effect on preoperative glycemic control in T2DM inpatients.
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