Effect of hyperbaric oxygen on early comprehensive rehabilitation of neonatal brain injury
DONG Wenjing1, ZHANG Weiwei2, ZHU Yaqin3
1.The Central Hospital of Wulanchabu, Wulanchabu, Inner Mongolia 012000,China; 2.The Third Medical Center of PLA General Hospital, Beijing 100039,China; 3. Yantai Special Treatment Sanatorium of the Chinese People’s Armed Police Force, Yantai 264000,China
Abstract：Objective To observe the therapeutic effect of hyperbaric oxygen therapy against neonatal brain injury caused by hypoxic and hypoxic encephalopathy.Methods The hyperbaric oxygen therapy for newborns with ischemic and hypoxic encephalopathy was started within 24 hours of admission (after the condition of a critically ill child became stable), with the oxygen concentration greater than 800 ml/L, oxygen therapy of 60 min, 1 time/d, and the treatment lasting for seven consecutive days.Results After the hyperbaric oxygen therapy, the percentage of consciousness, muscle tension, abnormal primitive reflex, and convulsion among these newborns was 13.95%, 25.58%, 11.63% and 16.28% in the intervention group, significantly lower than 25.58%, 39.53%, 27.91% and 32.56% of the control group. Newborns with abnormal NBNA scores accounted for 41.86% in the intervention group, significantly lower than 62.79% of the control group. CT results showed that newborns with cerebral edema made up 23.26% of the intervention group, significantly lower than 44.19% of the control group.Conclusions Hyperbaric oxygen can be used to treat neonatal brain injury, reverse neuronal death and improve the prognosis of children.
2019, Vol. 30 
