Abstract：Objective To study the therapeutic effect of hormone combined with an individualized drug therapy against non-arteritic anterior ischemic optic neuropathy (NAION). Methods A total of 56 cases(61 eyes) diagnosed with NAION between January 2012 and December 2015 were selected. According to etiology,oneset time of disease and results of ocular examination,visual field examination and fundus fluorescence angiography(FFA), treatment regimens were chosen that involved hormone combined with individualized medication. Improvements of visual acuity、visual fields and FFA after treatment were observed. The overall curative effect was evaluated. Results Vision was improved in each of the 56 cases (61 eyes)after treatment.Before treatment, characteristic changes of the visual field were detected in all the 61 eyes. After treatment, the range of the visual field defect was reduced by at least 30° in 48 eyes, and the effective rate was 78.7%. FFA confirmed 56 cases of characteristic changes in fluorescein angiography before treatment. After treatment, the fluorescein angiography was significantly improved in 54 eyes, and the effective rate was 88.5%. Conclusions The treatment of NAION with hormone combined with individualized medication can considerably improve the prognosis of patients.
Miller N R,Arnold A C.Current concepts in the diagnosis,pathogenesis and management of nonarteritic anterior ischaemic optic neuropathy[J].Eye (Lond),2015,29(1):65-79.
2020, Vol. 31 
