Abstract：Objective To compare perioperative indexes, renal function indexes and prognosis of patients with renal tumor after retrolaparoscopic partial nephrectomy and radical nephrectomy. Methods A total of 118 patients with stage cT1-T2 renal tumor admitted to Characteristics Medical Center of Chinese People’s Armed Police Force from January 2019 to April 2022 were selected to undergo radical laparoscopic nephrectomy (62 cases in the control group) and partial nephrectomy (56 cases in the observation group) according to their wishes. The indexes of operation, inflammatory factors, cellular immunity, renal function, postoperative complications and prognosis were compared between the two groups. Results The observation group had smaller tumor diameter, lower R.E.N.A.L. score and longer operation time, and the differences were statistically significant compared with the control group (P<0.05).There was no statistically significant difference in inflammatory cytokines or cellular immune indexes between the two groups before and 24 h after surgery (P>0.05).After surgery, the levels of BUN and SCR decreased and eGFR increased in the observation group, with statistically significant differences compared with the control group (P<0.05).At the last follow-up, the percentage of eGFR decrease in the observation group (10.24%) was lower than that in the control group (33.81%).The incidence of cardiovascular events and deaths in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusions Compared with retrolaparoscopic radical nephrectomy, retrolaparoscopic partial nephrectomy does not increase perioperative risk in patients with renal tumor and improve prognosis by preserving more renal function.
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2023, Vol. 34 
