|
|
Comparison of clinical effects of different bioactive pulp capping materials in immature permanent teeth pulpotomy |
YU Yanling1, ZHANG Jingyu1, DUAN Haijie1, MENG Nan1, WANG Yamei1, CHEN Fei2 |
1. Department of Stomatology, Qinhuangdao Harbor Hospital, Qinhuangdao 066000, China; 2. Department of Stomatology, the First Medical Center of PLA General Hospital, Beijing 100853, China |
|
|
Abstract Objective To study the clinical effects of different bioactive pulp capping materials used in the treatment of immature permanent teeth with irreversible pulpitis. Methods A total of 126 children (142 immature permanent teeth) diagnosed with irrecoverable pulpitis were selected from the Stomatology Department of Qinhuangdao Harbor Hospital from December 2021 to December 2022. They were numbered according to the order of treatment and randomly divided into 3 groups, Group A (42 cases, 49 teeth) were treated with iRoot BP Plus pulpotomy, Group B (42 cases, 46 teeth) were treated with Biodentine pulpotomy, and Group C (42 cases, 47 teeth) were treated with mineral trioxide condensate (MTA) pulpotomy. Visual analogue scale (VAS) was used to evaluate the pain degree of the children in each group at 24 and 72 hours after surgery, and the success rate, dentin bridge formation rate, tooth discoloration rate and gingival health status of the three groups were compared at 3, 6 and 12 months after surgery to evaluate the efficacy of the three groups. Results No moderate or severe pain occurred in all groups at 24h and 72h after operation, and there was no significant difference in the incidence of mild pain at 24 h among all groups (P>0.05). There were no significant differences in the success rate, dentin bridge formation rate or gingival health status among all groups during the same follow-up period (P>0.05). During the follow-up period, the discoloration rate of teeth in each group was recorded 3 months, 6 months and 12 months after surgery as follows, 3 months: Group A (0%), Group B (2.22%) , Group C (45.65%), 6 months: Group A (2.17%) , Group B (2.44%), Group C (54.55%), 12 months: Group A (4.55%), Group B (4.88%), Group C (69.77%), there was no significant difference between Group A and Group B (P>0.05), the differences between group A and group C, group B and group C were statistically significant (P<0.05). Conclusions The application of bioactive pulp capping materials in the treatment of immature permanent teeth with irrevocable pulpitis has low incidence of postoperative pain, mild degree, satisfactory clinical effect and no significant difference. The tooth discoloration rate of iRoot BP Plus and Biodentine is significantly lower than that of MTA.
|
Received: 02 January 2024
|
|
|
|
|
[1] |
Tzanetakis G N, Papanakou S, Koletsi D, et al. Outcome of partial pulpotomy in immature permanent teeth with symptomatic irreversible pulpitis: a prospective case series assessment[J]. J Endod, 2023, 49(9):1120-1128.
|
[2] |
Murray P E. Review of guidance for the selection of regenerative endodontics, apexogenesis, apexification, pulpotomy, and other endodontic treatments for immature permanent teeth[J]. Int Endod J, 2023, 56 Suppl 2:188-199.
|
[3] |
何文喜, 余 擎. 牙髓炎的活髓保存及再生治疗新进展:从基础到临床[J]. 中华口腔医学杂志, 2022, 57(1):16-22.
|
[4] |
肖 文, 史文涛, 汪 俊. 炎性活髓保存在年轻恒牙不可逆性牙髓炎及根尖周炎治疗中的应用[J]. 中华口腔医学杂志, 2022(3):287-291.
|
[5] |
Boutsiouki C, Frankenberger R, Krämer N. Clinical and radiographic success of (partial) pulpotomy and pulpectomy in primary teeth: A systematic review[J]. Eur J Paediatr Dent, 2021, 22(4):273-285.
|
[6] |
陈嘉琪, 董艳梅. 龋源性露髓成熟恒牙活髓保存治疗的研究进展[J]. 中华口腔医学杂志, 2022(01):95-100.
|
[7] |
Sadaf D. Success of coronal pulpotomy in permanent teeth with irreversible pulpitis: an evidence-based review[J]. Cureus, 2020, 12(1):e6747.
|
[8] |
Parirokh M, Torabinejad M, Dummer P M. Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview-part I: vital pulp therapy[J]. Int Endod J, 2018, 51(2):177-205.
|
[9] |
杜智敏, 印晶晶, 苗雷英. 三种盖髓剂用于恒牙活髓保存治疗疗效的Meta分析[J]. 现代口腔医学杂志, 2022, 36(06):396-403.
|
[10] |
Adıgüzel M, Ahmetoglu F, Eldeniz A, et al. Comparison of cytotoxic effects of calcium silicate-based materials on human pulp fibroblasts Mehmet[J]. J Dent Res Dent Clin Dent Prospects, 2019, 13(4):241-246.
|
[11] |
Sanz J L, Forner L, Llena C, et al. Cytocompatibility and bioactive properties of hydraulic calcium silicate-based cements (hcscs) on stem cells from human exfoliated deciduous teeth (sheds): a systematic review of in vitro studies[J]. J Clin Med, 2020, 9(12):3872.
|
[12] |
彭楚芳, 赵玉鸣, 杨 媛, 等. 三氧化矿物凝聚体牙髓切断术治疗年轻恒牙不可复性牙髓炎的初步研究[J]. 中华口腔医学杂志, 2015(12):715-719.
|
[13] |
周学东, 黄定明, 刘建国, 等. 牙髓损伤的活髓保存治疗[J]. 华西口腔医学杂志, 2017, 35(4):339-347.
|
[14] |
郎雪莲, 胡 涛. 恒牙活髓切断术-从基础到临床的新进展[J]. 口腔医学研究, 2023, 39(10):866-870.
|
[15] |
Guideline on pulp therapy for primary and immature permanent teeth[J]. Pediatr Dent, 2016, 38(6):280-288.
|
[16] |
Ricucci D, Loghin S, Siqueira J F, Jr. Correlation between clinical and histologic pulp diagnoses[J]. J Endod, 2014, 40(12):1932-1939.
|
[17] |
Tsukiboshi M, Ricucci D, Siqueira J F, Jr. Mandibular premolars with immature roots and apical periodontitis lesions treated with pulpotomy: report of 3 cases[J]. J Endod, 2017, 43(9s):S65-s74.
|
[18] |
Tong H J, Seremidi K, Stratigaki E, et al. Deep dentine caries management of immature permanent posterior teeth with vital pulp: a systematic review and meta-analysis[J]. J Dent, 2022, 124:104214.
|
[19] |
Cushley S, Duncan H F, Lappin M J, et al. Efficacy of direct pulp capping for management of cariously exposed pulps in permanent teeth: a systematic review and meta-analysis[J]. Int Endod J, 2021, 54(4):556-571.
|
[20] |
Camilleri J. Staining potential of Neo MTA plus, MTA plus, and biodentine used for pulpotomy procedures[J]. J Endod, 2015, 41(7):1139-1145.
|
[21] |
Mozyńska J, Metlerski M, Lipski M, et al. Tooth discoloration induced by different calcium silicate-based cements: a systematic review of in vitro studies[J]. J Endod, 2017, 43(10):1593-1601.
|
[22] |
Camilleri J. Characterization of hydration products of mineral trioxide aggregate[J]. Int Endod J, 2008, 41(5):408-417.
|
[23] |
Chen Y, Chen X, Zhang Y, et al. Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis[J]. BMC Oral Health, 2019, 19(1):227.
|
[24] |
Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review-Part Ⅲ: Clinical applications, drawbacks, and mechanism of action[J]. J Endod, 2010, 36(3):400-413.
|
[25] |
Vallés M, Roig M, Duran-Sindreu F, et al. Color stability of teeth restored with biodentine: a 6-month in vitro study[J]. J Endod, 2015, 41(7):1157-1160.
|
[26] |
Sheng M, Zhang D, Yan J, et al. Relationship between time to hemostasis and outcomes of pulpotomy using iRoot BP plus in symptomatic young permanent teeth: a prospective study[J]. J Clin Pediatr Dent, 2023, 47(6):142-149.
|
[27] |
Taha N A, Abdulkhader S Z. Full pulpotomy with biodentine in symptomatic young permanent teeth with carious exposure[J]. J Endod, 2018, 44(6):932-937.
|
[28] |
钟婉金, 李月梅, 陈婵婵, 等. iRoot BP Plus乳磨牙活髓切断术3年疗效观察[J]. 口腔医学研究, 2022, 38(7):669-672.
|
[29] |
尹世海. 髓腔穿孔的修复现状及策略[J]. 华西口腔医学杂志, 2018, 36(5):469-474.
|
[30] |
Zhou W, Zheng Q, Tan X,et al. Comparison of mineral trioxide aggregate and iroot bp plus root repair material as root-end filling materials in endodontic microsurgery: a prospective randomized controlled study[J]. J Endod, 2017, 43(1):1-6.
|
[31] |
Dahlander A, Soares F, Grindefjord M, et al. Factors associated with dental fear and anxiety in children aged 7 to 9 years[J]. Dent J (Basel), 2019, 7(3):68.
|
[32] |
Careddu R, Duncan HF. A prospective clinical study investigating the effectiveness of partial pulpotomy after relating preoperative symptoms to a new and established classification of pulpitis[J]. Int Endod J, 2021, 54(12): 2156- 2172.
|
[33] |
Eggmann F, Ayub J M, Conejo J, et al. Deep margin elevation-present status and future directions[J]. J Esthet Restor Dent, 2023, 35(1):26-47.
|
[34] |
赵思铭, 王晓燕. 洞缘设计对CAD/CAM瓷嵌体边缘质量和边缘适应性及微渗漏的影响[J]. 北京大学学报(医学版), 2023, 55(6):1105-1110.
|
|
|
|