血小板与淋巴细胞比值对糖尿病神经源性膀胱的诊断价值

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Abstract Objective To analyze the relationship between the value of platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) in the diagnosis of diabetic neurogenic bladder. Methods The clinical data of 138 patients with diabetic neurogenic bladder and 307 patients with type 2 diabetes mellitus diagnosed in the 909th Hospital from January 2019 to December 2022 were retrospectively analyzed. Logistic regression was used to analyze the independent risk factors for diabetic neurogenic bladder development. The receiver operating characteristic curve (ROC) was used to analyze the risk factors to the diagnostic efficacy of diabetic neurogenic bladder. Results Compared with the simple diabetes mellitus group, the diabetic neurogenic bladder group had a higher proportion of women, older age, a longer history of diabetes, a higher proportion of diabetic nephropathy and atherosclerosis, and a higher level of fasting blood glucose, PLR, NLR and blood urea nitrogen. The proportion of BMI, smoking history and drinking history was lower, and the levels of erythrocyte, hemoglobin, total bilirubin, direct bilirubin, indirect bilirubin, albumin and uric acid were even lower (P<0.05). Long history of diabetes [OR=1.127, 95% CI(1.037-1.223), P=0.003]and an elevated PLR [OR=1.408, 95% CI(1.130-1.753),P=0.001] were independent risk factors for diabetic neurogenic bladder development, while low levels of total bilirubin [OR=0.881, 95% CI(0.792-0.979),P=0.021] and decreased hemoglobin [OR=0.956, 95% CI(0.924-0.988),P=0.007] were protective factors. The result of ROC showed that the maximum area under the curve of PLR was 0.897, and the best diagnostic cut point was 101.19, at which time the sensitivity and specificity were 83.3% and 76.6% respectively. Conclusions PLR and NLR values of patients with diabetic neurogenic bladder are higher than those of patients with diabetes mellitus alone. PLR is valuable in the diagnosis of neurogenic bladder in diabetic patients.

Key words： diabetes mellitus neurogenic bladder inflammation platelet lymphocyte

Received: 16 October 2023

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	Articles by authors
	FANG Xiaoyan
	ZENG Yanhe
	LIN Xiaoying
	LIN Zhengkun
	HE Suling
	RUAN Jing

Cite this article:

FANG Xiaoyan,ZENG Yanhe,LIN Xiaoying等. Value of platelet to lymphocyte ratio in diagnosis of diabetic neurogenic bladder[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2024, 35(6): 493-496.

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https://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR https://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2024/V35/I6/493

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