TyG指数对急性心肌梗死患者院内不良心血管事件的预测价值

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Abstract Objective To investigate the association between the triglyceride-glucose(TyG) index and in-hospital major adverse cardiovascular events(MACE) in patients with acute myocardial infarction(AMI) based on propensity score matching (PSM) method. Methods A retrospective analysis was conducted on 769 AMI patients admitted to the First Medical Center of PLA General Hospital from January 2022 to May 2024. The patients were divided into non-MACE and MACE groups based on the occurrence of MACE. PSM was used for 1:1 matching to balance the baseline data between the two groups. Clinical data after matching were compared, and the relationship between the TyG index and in-hospital MACE in AMI patients was analyzed using multivariable logistic regression. Results A total of 132 patients experienced in-hospital MACE. Before PSM, there were significant differences in age, smoking history, drinking history, diabetes history, and stroke history between the two groups (P<0.05). After PSM, 258 cases were obtained, and the comparison between the groups was balanced. After PSM, the MACE group had higher levels of heart rate, C-reactive protein (CRP), N-terminal pro-B-type natriuretic peptide (NT-proBNP), TyG index, and higher proportions of renal dysfunction, liver dysfunction, intra-aortic balloon pumping(IABP), and extracorporeal membrane oxygenation (ECMO), while the systolic blood pressure(SBP), hemoglobin(Hb), albumin levels, and the proportion of temporary pacemaker use were lower (P<0.05). Multivariable logistic regression analysis showed that after adjusting for confounding factors, TyG index [OR and 95% CI: 1.96(1.23-3.13)] was still the influential factor for MACE in hospital (P<0.05). Conclusions The incidence of in-hospital MACE of AMI patients increases with the elevation of the TyG index, and the TyG index is an independent influencing factor of the former.

Key words： triglyceride-glucose index acute myocardial infarction in-hospital adverse outcome

Received: 04 September 2024

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	ZHOU Xiang
	LIU Ruihan
	LIU Yutong
	TIAN Fan
	ZHANG Jie
	WANG Xiaomao
	CAO Jian

Cite this article:

ZHOU Xiang,LIU Ruihan,LIU Yutong等. Prognostic value of TyG index for in-hospital adverse cardiovascular events in patients with acute myocardial infarction[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2025, 36(1): 25-29.

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https://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR https://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2025/V36/I1/25

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