临床药师协作规范:普外科预防使用抗菌药物的效果分析

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (946 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the important role of pharmacists in standardizing the prophylactic antimicrobial applications in general surgery. Methods The clinical data of 136 patients undergoing Class I and II incision surgery admitted to the General Surgery Department of Jiangxi Armed Police Corps Hospital from January 2021 to December 2023 were retrospectively analyzed. Based on the pharmacist’s intervention in the prophylactic use of antimicrobials, the patients were divided into an intervention group (74 cases) and a control group (62 cases).Compare the differences between the two groups of patients in terms of the prophylactic antimicrobial use rate, the medication duration, the medication type, the administration time, the combination of medications, and the reasonable rate of prophylactic medication. Results Comparison of the basic conditions of the patients in the two groups showed no statistically significant differences (P>0.05), and the data were comparable. The prophylactic antimicrobial usage rate in the intervention group was 32.43%, compared to 88.71% in the control group; the rate of combined medication use was 4.05% in the intervention group and 20.97% in the control group; the rationality rate of prophylactic medication use was 72.97% in the intervention group and 17.74% in the control group, with statistically significant differences (P＜0.05). The intervention group demonstrated superior rationality in the duration, selection, and timing of prophylactic antimicrobial use compared to the control group. Conclusion Pharmacists play an important role in standardizing the prophylactic antimicrobial applications in general surgery, and the intervention measures demonstrating a positive impact.

Key words： intervention antibiotics perioperative period

Received: 18 March 2024

ZTFLH:

R969.3

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI Liang
	HUANG Yushu
	ZENG Peng

Cite this article:

LI Liang,HUANG Yushu,ZENG Peng. Analysis of the effectiveness of pharmacist collaboration in standardizing the prophylactic antimicrobial applications in general surgery[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2025, 36(1): 55-58.

URL:

https://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR https://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2025/V36/I1/55

[1]	国家卫生计生委办公室, 国家中医药管理局办公室, 总后卫生部药品器材局. 关于印发《抗菌药物临床应用指导原则(2015年版)的通知[S]. 国卫办医发
	[2015]43号, 2015,7,24.
[2]	谢朝云, 熊芸, 杨忠玲. 预防与非预防使用抗菌药物Ⅰ类切口手术患者感染病原菌分布及耐药性差异[J]. 中国消毒学杂志,2022,39(9):672-676.
[3]	Li X, Chen H, Zhu S, et al. Efficacy and feasibility of a collaborative multidisciplinary program for antibiotic prophylaxis in clean wound surgery[J]. Int J Clin Pharm, 2018,40(1):150-159.
[4]	万兵, 支玲姣, 徐佳立,等. 某医院Ⅰ类切口抗菌药物使用情况与分析[J]. 解放军药学学报, 2023,36(4):344-346.
[5]	张晶晶, 王凤玲, 孟祥云,等. PDCA循环对腹腔镜下胆囊切除术围手术期预防使用抗菌药物的影响效果分析[J]. 中国药房,2023,34(13):1632-1636.
[6]	吴孝安, 李小东, 孙伟,等. 加权TOPSIS法评价肝胆及胰腺手术预防性使用抗菌药物的合理性[J]. 中国医院药学杂志,2023,43(4):436-440.
[7]	郭秀芹, 赵秀平. 普通外科Ⅰ类切口抗菌药物预防使用干预及与手术部位感染相关性[J]. 中国感染控制杂志,2012,11(5):348-351.
[8]	中华人民共和国卫生部. 《抗菌药物临床应用管理办法》[J]. 中国感染控制杂志,2012,11(3):236-240.
[9]	肖永红. 《抗菌药物临床应用管理办法》简析[J]. 医药导报,2013,32(8):975-978.
[10]	张文华. 医院Ⅰ类切口围术期抗菌药物预防使用合理性分析[J]. 临床合理用药,2023,16(23):140-146.
[11]	高秀平, 彭朝辉, 陶任重. 预防性使用抗菌药物在肥胖患者开放腹股沟疝无张力修补术中的临床疗效[J]. 中华疝和腹壁外科杂志(电子版),2021,15(4):366-368.
[12]	郭芳芳, 李国庆, 周文. 老年腹外疝手术患者围术期预防性应用抗菌药物调查[J]. 中国老年学杂志,2012,32(21):4766-4767.
[13]	林冠文, 刘瑛, 李贵涛,等. 腹股沟疝修补术围手术期预防用抗菌药物专项整治效果[J]. 中国感染控制杂志,2014,13(7):402-404.
[14]	贾宏军, 郑晓辉, 赵振营. 新版《抗菌药物临床应用指导原则》(2015)的解读[J]. 天津药学,2016,28(5):46-48.
[15]	靳艳文, 叶辉, 李富宇,等. 抗菌药物与手术治疗单纯性急性阑尾炎的系统评价[J]. 重庆医学,2017,46(9):1235-1239.
[16]	陈立军, 彭靖, 马军亮,等. 急性结石性胆囊炎腹腔镜胆囊切除术预防性应用抗生素的疗效观察[J]. 中国普通外科杂志,2019,28(8):1018-1022.
[17]	王惠霞, 滕月鹏, 古殿杰. 抗菌药物专项整治前后我院腹腔镜胆囊切除术围术期抗菌药物预防性使用分析[J]. 中国药房,2015,26(5):579-582.
[18]	张翕, 杨瑶瑶, 周越,等. 我国省级抗菌药物临床应用分级管理目录分析[J]. 中国药房,2021,32(16):1921-1925.
[19]	王国权, 李丹, 吴琼. Ⅰ类手术切口抗菌药物使用干预效果分析[J]. 中华医院感染学杂志,2013,23(20):5032-5034.
[20]	Zhou L, Ma J, Gao J, et al. Optimizing prophylactic antibiotic practice for cardiothoracic surgery by pharmacists’ effects[J]. Medicine (Baltimore), 2016,95(9):e2753.

[1]	. [J]. Med. J. Chin. Peop. Armed Poli. Forc., 2024, 35(9): 790-792.