|
|
|
| Determination of effective content of polygonum multiflorum in lipid-lowering drink particles |
| LIU Qing，REN Deyu，CAO Xuedong, and LIU Lifeng. |
| Department of Pharmacy, Shanxi Provincial Crops Hospital, Chinese People's Armed Police Forces, Taiyuan 030006, China |
|
|
|
|
Abstract Objective To establish a method of determining the effective component of Polygonum multiflorum in lipid-lowering drink particles. Methods HPLC method was used with octadecyl silane bonded silica as a filler and with acetonitrile water(25∶75)as the mobile phase. The detection wavelength was set at 320 nm; the column temperature was 25 ℃ at a flow rate of 1.0 ml/min. Results 2,3,5,4- tetrahydroxy-stilbene-2-0-β-D -glucoside in the 0.05-0.625 μg range showed a good linear relationship. The sample separation was good, with no interference and sample stability in the negative was good. Conclusions The method is user-friendly and accurate with a good reproducibility. It can be used to determine the content of 2,3,5,4′-tetrahydroxy diphenyl ethylene-2-0-β-D-glucoside.
|
|
Received: 21 December 2011
|
|
|
|
|
|
| ［1］ |
曹学东，张志慧，姬瑾，等.降脂饮颗粒的制备及质量控制［J］.实用医技杂志,2008,15(31):4406-4408.［2］国家药典委员会.中华人民共和国药典2010年版（一部）［S］.北京：化学工业出版社：164.［3］薛爱华，宋文静.骨质丸中何首乌有效成分的测定［J］.天津中医药,2010,27(4):340-341.［4］张长林.HPLC测定养血颗粒中2,3,5,4′-四羟基二苯乙烯-2-O-β-D葡萄糖苷的含量［J］.中国中药杂志,2006,31(6)：1370-1371.［5］张元桐,姜泓,曲静,等.HPLC法测定制何首乌中2,3,5,4-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的含量［J］.中国药品标准,2006,7(3)：41-43.［6］赵玲，李雅莉，张丽，等.二苯乙烯苷对高胆固醇血症致β-淀粉样肽增高大鼠模型的影响［J］.中国药理学通报,2005，21（1）：49-51.［7］高瑄，胡英杰，符林春.何首乌二苯乙烯苷的调节血脂作用［J］.中国中药杂志，2007，32（4）：323-324.［8］胡存华，赵立波，王晓敏，等.二苯乙烯苷增强正常血管内皮细胞抗氧化作用研究［J］.医药导报，2007，26（2）：138-140.
|
|
|
|
