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Pathological analysis of liquid-based cytological diagnosis in fine needle aspiration of thyroid lesion |
WANG Yuxin1, WU Weiguo2,HAN Yanhua3, and SONG Zonghai4. |
1. Department of Pathology,
2. Medical Unit of First Detachment, Jilin Provincial Corps, Chinese People’s Armed Police Forces, Changchun 130052, China;
3. Department of Special Examination, Hospital of Jilin Provincial Corps, Chinese People’s Armed Police Forces, Changchun 130052, China;
4. Health Office of Logistic Department, Jilin Provincial Corps, Chinese People’s Armed Police Forces, Changchun 130052 |
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Abstract Objective To evaluate the liquid-based cytology in the diagnosis of thyroid diseases. Methods Two hundred cases of thyroid lesion in outpatient and inpatient departments underwent liquid-based cytological examinations to compare the quality and diagnosis of traditional manual smear preparation. Results The preserved specimens and smears made with liquid-PREP showed an increased number of valuable cells, a cleaner background, uniform distribution, less thyroid colloid in the smear and clear nuclei. The positive rate of thyroid cancer was 6.55% (15/229) in liquid-PREP and 3.93% (9/229) in traditional manual smear preparation. Conclusions Liquid-PREP improves the smear quality and positive rate of cancer in thyroid fine needle aspiration cytology and can serve as a promising diagnostic method for thyroid lesion.
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Received: 02 January 2012
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