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| A study on risk factors in young patients with coronary heart disease |
| QUAN Yongjun1, ZHU Hang2, SU Xiaojun1, WANG Haotian3, HE kai4, ZHANG Ziyun5, , SUN Jinyan1 |
1. Medical College of Nankai University, Tianjin 300071, China;
2. Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China;
3. Medical Center of Tsinghua University, Beijing 100084, China;
4. Department of Cardiology, People’s Hospital of Chongqing Municipality,Chongqing 400053, China;
5. Department of Cardiology, Henan Honli Hospital, Changyuan 453400, China |
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Abstract Objective To study the risk factors in young patients with coronary heart disease. Methods A total of 855 patients (age≤40 years) hospitalized in this department between June 2011 and March 2013 were included in this study. Patients with definite diagnosis were as young coronary heart disease group (n=455) and other patients were as control group (n=400). Their serum homocysteine was measured by high performance liquid chromatography. The single factor analysis and multivariate logistic regression analysis were used for risk factors of young coronary heart disease. Results The serum Hcy, family history of coronary heart disease in young coronary heart disease group were all higher than those in control group(P<0.01 or P<0.05). The logistic regression analysis demonstrated that Hcy(OR=1.380,P=0.001)and history of coronary heart disease(OR=3.556,P=0.002)were all independent risk factors for young coronary heart disease patients. Conclusions High serum homocysteine and family history of CHD are independent risk factors for young CHD patients.
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Received: 24 December 2013
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2014, Vol. 25 
