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| Application of statins in patients with chronic heart failure |
| ZHAO Nannan1,LIU Yingping1,WANG Zhinan1,JIN Bin2,WANG Ping1,YANG Shuixiang1, REN Lihui1 |
1.Department of Cardiology,Beijing Shijitan Hospital Affiliated to the Capital Medical University,Beijing 100038,China;
2.Science School,Communication University of China,Beijing 100024,China |
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Abstract Objective To evaluate the effect of statins on chronic heant failure (CHF). Methods The clinical data in 100 patients with CHF from this hospital were collected, NYHA ClassⅡ-Ⅳ,and LVEF≤50%.According to whether statins were taken or not, the patients were assigned into two groups,and each group with 50 patients. The levels of left ventriculer end-dimension (LVEDD), left vewtricular end-rystohic climension(LVESD), LVEF, C-reactive protein (CRP), low-density lipoprotein cholesterol (LDL-C), NT-pro BNP, admission times and mortality were compar. Results 1. Compared with the control group, LVESD and LVEDD levels in the statins group significantly decreased (P<0.05), while LVEF was significantly increased(P<0.05).2.In the statins group, the CRP,LDL-C and NT-proBNP was dramatically decreased (P＜0.05),but there were no remarkably changes in control one.3.Admission times and mortality in two groups showed the difference(P<0.05) . Conclusions CHF based on cardiovascular disease with long-term use of statins has obvious benefit.
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Received: 01 September 2014
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2015, Vol. 26 
