高血压基底节区脑出血治疗中超早期经外侧裂入路对免疫功能的影响

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Abstract Objective To analyze ultra early transsylvian fissure in the effect on the immune function of the patients in the treatment of hypertensive cerebral hemorrhage in basal ganglia. Methods The retrospective analysis of the clinical data of an ultra early transsylvian fissure treatment of hypertensive cerebral hemorrhage in basal ganglia patients in this hospital from 2012 February to 2014 year in February 191 cases was carried out. The change in B lymphocyte, immunoglobulin and complement level before and after the treatment was observed. Results The patients before discharge CD19⁺-CD25⁺(0.91%±0.29%), CD19⁺-CD25^-(10.74%±2.33%) decreased significantly after admission (P＜0.05), the total number of lymphocytes was not statistically significant; before and after the IgA, IgG, IgM and C₃ levels were not statistically significant. 191 patients obtained effective follow-up, 2 patients died, all because of pulmonary infection. ADL grade: Ⅰ grade 43 cases, Ⅱ grade 101 cases, 35 cases of grade Ⅲ, 7 cases of grade IV, 3 cases of grade V, with an efficiency of 94.7% (179/189). Conclusions Ultra early transsylvian approach can effectively improve the humoral immune disorder in patients with hypertensive cerebral hemorrhage in basal ganglia, but has no significant effect on the immunoglobulin and complement level, in the clinical treatment. In the future, we should focus on immunoglobulin and complement levels of improvement, in order to further improve the prognosis of the patients.

Key words： ultra early lateral fissure approach hypertensive cerebral hemorrhage in basal ganglia immune function influence

Received: 15 June 2016

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2016/V27/I9/881

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