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Clinical features and epidemiological characteristics and strategies of control of an outbreak of measles in a college |
MA Fuying, ZHU Zhangtao, WAN Juan, WANG Ziyun, ZHANG Wenjing, CUI Xiaoli, LIU Shilei, YIN Chongyang, and WANG Haitao |
Department of Infectious Diseases, General Hospital of Chinese People’s Armed Police Force, Beijing 100039, China |
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Abstract Objective To study the epidemiological characteristics, clinical features and strategies of control of fifteen outbreaks of measles in a college.Methods The epidemiological and clinical data of 15 cases of measles was investigated, samples were taken, the cause of these outbreaks was analyzed, and the epidemiological characteristics and strategies of control were analyzed.Results The outbreaks of measles mostly occurred in spring. The clinical characteristics included fever, rash, pharyngalgia, cough, a running nose, a stuffy nose, and oral leukoplakia. One of the patients developed pneumonia and conjunctivitis, and another one developed myocarditis. Measles virus nucleic acid was positive in 13 cases. As for epidemiological characteristics, the first case occurred on April 1 2015,the peak of the epidemic occurred between April 13 and April 17, and the epidemic ended on April 17. Cases of infection of the second generation were concentrated in the longest incubation period. Eleven of these patients had definite epidemiological contact with measles, accounting for 73% of the patients.These patients of measles mostly lived in three dormitories on the same floor. They were all males, aged 19 to 25.Conclusions The outbreak of measles was associated with the season, vaccination, age of disease onset, and control strategies. It is recommended that clinical doctors be alert to sporadic cases of measles in spring in colleges and densely-populated neighborhoods, isolate the measles patients immediately, vaccinate those who have close contact with measles patients, and guard against outbreaks of measles.
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Received: 05 November 2016
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[1] |
艾静文,张文宏.我们离麻疹消除还有多远?[J].微生物与感染,2016,11(1):8-11.
|
[2] |
中疾控发[2014]36 号.《中国疾病预防控制中心关于印发全国麻疹监测方案的通知》(S)2014.
|
[3] |
北京疾控发《北京市麻疹和风疹联合监测方案(2015)》(S)2015.
|
[4] |
Michel Y,Saloum K,Tournier C,et al.Rapid molecular diagnosis of measles virus infection in an epidemic setting [J].J Med Virol,2013,85(4):723-730.
|
[5] |
World Health Organization[J].Measles, Fact sheet No 286. 2013.
|
[6] |
Sudfeld C R,Navar A M,Halsey N A.Effectiveness of measles vaccination and vitamin A treatment[J].Int J Epidemiol,2010,39(Suppl 1):S48-55.
|
[7] |
Demicheli V,Rivetti A,Debalini M G,et al.Vaccines for measles,mumps and rubella in children[J].Cechranc Database Syst Rev,2012,2:CD004407.
|
[8] |
Barrabeig I,Rovira A,Rius C,et al.Effectiveness of measles vaccination for control of exposed children[J].PediatrInfect Dis J,201l,30(1):78-80.
|
[9] |
范 娟,李 茂,军吴青,等.儿童麻疹的临床管理—美国传染病学会2015年报告简介[J].中华实用儿科临床杂志, 2015,30(22):1684-1686.
|
[10] |
陈灏珠.实用内科学[M].13版.北京:人民卫生出版社,2009:423-428.
|
[11] |
邢建刚,李全瑞,王 晶. 85 例麻疹患者的临床分析[J].中国医刊,2015,50(12):39-41.
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