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Multi-factor regression analysis of 30-day mortality in patients with spontaneous intracranial hemorrhage |
CAI Genping, WANG Wenhao, HU Kang, LIU Changchun, LIN Hong, and ZHANG Yuan |
Department of Neurosurgery, No.175 Hospital of PLA,Zhangzhou 363000, China |
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Abstract Objective To explore the risk factors of 30-day mortality in patients with spontaneous intracranial hemorrhage (SIH).Methods Three hundred and twenty-four patients with SIH admitted to our hospital between January 2012 and January 2016 were retrospectively studied. Eight-two patients who died within 30 days were assigned to a death group, while another 242 survivors were assigned to a survival group. The main clinical features of both groups were observed. Univariate and multivariate logistic regression analysis was used to study such risk factors for death as a decrease of Glasgow coma score, diabetes, cerebellar hemorrhage, an increased amount of hemorrhage and intraventricular hemorrhage.Results When compared with the survival group, patients in the death group had significantly older ages (54.38±12.47 vs 51.73±11.94, P=0.028), a higher rate of hypertension (68.29% vs 55.79%, P=0.047),diabetes (46.34% vs 27.69%, P=0.002)and of smoking (35.37% vs 21.07%, P=0.009). The rate of cerebellar hemorrhage increased apparently (20.73% vs 8.68%, P=0.003), the rate of intraventricular hemorrhage increased significantly (74.39% vs 54.96%, P=0.002), the surgical rate decreased (20.73% vs 37.19%, P=0.006), the amount of bleeding increased apparently [(110.98±36.96)ml vs (77.04±31.81)ml, t=4.922, P=0.000] and the Glasgow coma score decreased significantly (7.52±2.70 vs 9.54±2.06,t=4.207,P=0.000).Conclusions A decrease in Glasgow coma scale, diabetes, cerebellar hemorrhage, an increased amount of hemorrhage and cerebral ventricular hemorrhage are risk factors for 30-day mortality in patients with SIH.
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Received: 10 December 2016
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