2012-2016年本医院内获得性肺炎病原菌分布及革兰阴性杆菌耐药性分析

Abstract
Figure/Table
References
Related Citation (5)

Download: PDF (681 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To analyze both the distribution of pathogens that cause hospital acquired pneumonia and drug resistance of gram-negative bacteria in a hospital. Methods Pathogens of hospital-acquired pneumonia were collected from 2012 to 2016. The drug resistance of gram-negative bacteria was detected with MIC and evaluated according to the criteria of Clinical and Laboratory Standard Institute of America (CLSI). Results Among these pathogens of hospital-acquired pneumonia, gram-negative bacteria were common and the top three organisms were Pseudomonas aeruginosa, Klebsiella pneumoniae, and Baumanii, accounting for 17.38%, 17.30%, and 15.98%, respectively. Among gram-positive bacteria, Staphylococcys aureus was common. In these pathogens, fungus accounted for 12% to 15% of acquired respiratory tract infections.Pseudomonas aeruginosa was the most sensitive to amikacin (87.76%-95.56%). The sensitivity of Klebsiella pneumoniae to meropenem and imipenem decreased year by year.The sensitivity of Baumanii to other antimicrobial agents was low except amikacin (63.64%-84.78%). Conclusions The detection rate of multi-drug resistance of Pseudomonas aeruginosa and Baumanii is beginning to decrease significantly. Klebsiella pneumoniae, which produces ESBL and carbon-resistant penicillium, is worthy of attention. Regular and prudent surveillance of the distribution of pathogens responsible for hospital acquired pneumonia and drug resistance can help clinicians to treat and prevent HAP.

Key words： hospital-acquired pneumonia bacterial distribution bacterial resistance surveillance gram-negative bacteria

Received: 07 August 2017

ZTFLH:

R373.1

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI Bei
	LUO Wenling
	XIE Xiaoyue
	HUANG Ligang
	YAN Feng

Cite this article:

LI Bei,LUO Wenling,XIE Xiaoyue等. Distribution of pathogens for hospital acquired pneumonia and drug resistance analysis of gram-negative bacteria[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(11): 1151-1154.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2017/V28/I11/1151

[1]	Plagov A, Mejias L, Piazza Y, et al . Validation of Beckman Coulter AU680 Analyzers: Utility of Clinical Laboratory Standards Institute (CLSI) C28~A3[J]. Am J Clin Pathol, 2014, 142(suppl_1): A042-A042.
[2]	胡付品,朱德妹,汪复,等.2011年中国CHINET细菌耐药性监测 [J].中国感染与化疗杂志,2012,12(5):321-329.
[3]	汪复,朱德妹,胡付品,等. 2012年中国CHINET细菌耐药性监测 [J].中国感染与化疗杂志,2013,13(5):321-330
[4]	胡付品,朱德妹,汪复,等.2013年中国CHINET细菌耐药性监测 [J].中国感染与化疗杂志,2014,14(5):369-378.
[5]	胡付品,朱德妹,汪复,等.2014年中国CHINET细菌耐药性监测 [J].中国感染与化疗杂志,2015,15(5):401-410.
[6]	杨青,俞云松,孙自镛,等. 2011年中国CHINET呼吸道病原菌分布和耐药性监测 [J].中国感染与化疗杂志,2013,13(5):357-364.
[7]	管婧,卓超,苏丹虹,等. 2012年中国CHINET克雷伯菌属细菌耐药性监测 [J]. 中国感染与化疗杂志,2014,14(5):398-404.
[8]	李耘,吕媛,薛峰,等.2015年全国细菌耐药监测报告[J].中国执业药师,2016,13(3):3-8.
[9]	刘一力,石毅.2010~2014年鲍曼不动杆菌临床分布及耐药性分析[J].国际检验医学杂志,2015,36(13):1899-1904.
[10]	张辉,张小江,徐英春.2012年中国CHINET不动杆菌属细菌耐药性监测[J].中国感染与化疗杂志,2015,14(5):392-397.