2型糖尿病患者血糖波动与抑郁状态的相关性

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Abstract Objective To explore the correlations between blood glucose fluctuation and depression in patients with type 2 diabetes mellitus.Methods A total of 42 patients with type 2 diabetes mellitus were monitored for 72 h with the continuous glucose monitoring system (CGMS) between August 2015 and September 2016.Another 28 volunteers who matched the subjects in age and gender were chosen as the control. The Montgomery-Asberg depression rating scale (MADRS) was used to assess the score. MADRS scores and blood glucose fluctuation parameters were compared between the two groups, and the correlations between blood glucose fluctuation parameters and MADRS in the T₂DM group were analyzed.Results The MADRS score was (15.67±7.43) in the T₂DM group, but was (8.29±3.76) points in the control group, so the difference was statistically significant (t=4.818,P<0.01). Compared with the control group, MAGE, SDBG, LAGE, MODD and MPPGE in the T₂DM group were significantly increased, and the difference was also statistically significant (P<0.01). MADRS scores were positively correlated with blood fluctuation (MAGE) (r=0.330,P<0.05)in the T₂DM group.Conclusions Blood glucose fluctuations (MAGE) are associated with depression in patients with type 2 mellitus.

Key words： type 2 diabetes mellitus blood fluctuation depression

Received: 20 August 2017

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	Articles by authors
	WU Jinxiao
	GE fei
	CAO Yi
	XU Xiuping
	LV Xiaofeng

Cite this article:

WU Jinxiao,GE fei,CAO Yi等. Relationships between blood glucose fluctuation and depression in patients with type 2 diabetes mellitus[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(1): 45-47.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2018/V29/I1/45

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