平阳霉素碘油乳剂栓塞治疗肝海绵状血管瘤对肝功能的影响

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Abstract Objective To investigate the influence of Pingyang mycin-lipiodol emulsion on liver function in patients with hepatic cavernous hemangioma.Methods Sixty-two hepatic cavernous hemangioma patients who had complete follow-up data were treated with interventional therapy in our hospital between March 2010 and December 2016. The changes of test results regarding alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ- glutamyl transferase (GGT), alkaline phosphatase (ALP), total bilirubin(TBIL), direct bilirubin(DBIL) and indirect bilirubin(IBIL) were retrospectively analyzed with statistical methods before interventional embolization and three days and two weeks after embolization.Results The levels of TBIL,DBIL,ALT and AST were separately (16.33±6.66)μmol/L,(3.63±2.08)μmol/L,(80.09±82.63) U/L and(40.31±19.46)U/L three days after embolization. There was significant difference(P<0.05). After two weeks, ALT,AST,TBIL,DBIL and IBIL were (16.14±6.38)U/L,(17.97±4.54 U/L),(12.17±4.68)μmol/L and(2.13±1.09)μmol/L respectively, and the difference was not statistically significant when compared to the preoperative results. GGT, ALP and IBIL did not change significantly after treatment.Conclusions Embolization with Pingyang mycin-lipiodol emulsion in hepatic cavernous hemangioma patients can result in transient increase of ALT, AST, TBIL and DBIL. Liver function tests can return to normal usually within two weeks. There are no serious complications of biliary duct damage.

Key words： hepatic cavernous hemangioma embolization bilirubin transaminase

Received: 20 October 2017

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	HU Yuefeng
	ZHANG Qiang
	WANG Hongyan

Cite this article:

HU Yuefeng,ZHANG Qiang,WANG Hongyan. Influence of Pingyang mycin-lipiodol emulsion on liver function in patients of hepatic cavernous hemangioma[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(3): 247-249.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2018/V29/I3/247

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