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Clinical analysis of 23 cases with uterine smooth muscle tumors of uncertain malignant potential |
CHEN Yuan, WANG Shuhe |
Department of Gynecology,Army General Hospital,Beijing 100700,China |
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Abstract Objective To investigate the clinical symptoms、manifestations and methods of auxiliary examination and diagnosis of uterine smooth muscle tumor of uncertain malignant potential(STUMP).Methods All the cases were selected from patients who had received surgery in the Army General Hospital between January 2009 and December 2015. The original surgical specimens of the patients were reviewed by pathologists using the same diagnostic criteria. Our study only included patients who were re-diagnosed as STUMP and represented spindle cell type differentiation. Detailed data was obtained by reviewing the medical records. Retrospective analysis was conducted in this study.Results Twenty-three patients were collected. All the patients were of childbearing age or peri-menopausal women. Most of the patients ranged from 41 to 50 in age (accounting for 60.9%). Patients who suffered from STUMP had similar symptoms to those with uterine leiomyoma or leiomyosarcoma,but menorrhagia and menostaxis were the most common symptoms (56.5%). Twenty-two of these cases of STUMPs were classified as benign uterine leiomyomas by ultrasound examination,while 1 case of STUMP was diagnosed as a big ovarian tumor before surgery. The tumors mostly grew between the intramural walls of the uterine body (60.9%) , and the maximum diameter ranged from 2cm to 16cm, with an average of 6.4cm. All the STUMPs had a similar appearance to benign leiomyomas.Conclusions The age distribution、clinical symptoms、pelvic ultrasound images of the patients with STUMP are more similar to those who have leiomyomas. Definite diagnosis still depends on pathological examination.
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Received: 01 November 2017
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