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| Effects of antibiotics on inflammatory markers of colorectal polyps after surgery via argon plasma coagulation and electrocoagulation |
| ZHANG Xingguang, XIE Liqun, DENG Quanjun, ZHAO Jianye, ZHAO Junyan, CHEN Jinmei, and GENG Liyuan |
| Department of Gastroenterology, Affiliated Hospital of Logistics University, Chinese People’s Armed Police Force,Tianjin 300162, China |
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Abstract Objective To explore the effect of antibiotics on inflammatory markers of colorectal polyps after surgery by means of argon plasma coagulation and electrocoagulation.Methods In this prospective study, 58 cases of patients with colorectal polyps received the endoscopic treatment. These patients were randomly divided into the antibiotic group (28 cases) and the non-antibiotic group (30 cases). The levels of plasma endotoxin, procalcitonin and C-reactive protein were measured before endoscopic treatment and one day, three days after treatment.Results No hemorrhage or perforation occurred in any of the cases after postpolypectom . The abdominal pain and abdominal distension occurred in nine cases (15.5%) after postpolypectomy, but the symptoms disappeared in twelve to twenty-four hours. Low fever after polypectomy occurred in one case (3.6%) in the antibiotic group, and the interval between polypectomy and the occurrence of fever was eight hours. Fever occurred after polypectomy in four of the thirty cases (13.3%) in the non-antibiotic group, and the median interval was seven to fourteen hours. There was significant difference between the two groups in the incidence of fever (P<0.05). The difference in plasma levels of endotoxin, procalcitonin and C-reactive protein was not statistically significant one day and three days after endoscopic treatment compared with preoperative levels in the two groups.Conclusions Colorectal polypectomy using argon plasma coagulation techniques and electric coagulation is considered safe. The inflammatory markers after endoscopic treatment are basically normal. Antibiotics should be used with caution.
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Received: 20 December 2017
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2018, Vol. 29 
