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Predictive value of TIMI risk scores for long-term prognosis in patients with acute myocardial infarction |
XI Ke1, LIU Hui1, WANG Li2 |
1.Department of Headquarters,the Third Medical Center,Chinese PLA General Hospital, Beijing 100089, China; 2. Department of Medical,Beijing Public Security Hospital, Beijing 100121, China |
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Abstract Objective To investigate the predictive value of TIMI risk scores for thrombolytic therapy of myocardial infarction in patients with acute myocardial infarction.Methods The present data was obtained from a retrospective analysis. A total of 2958 cases of acute myocardial infarction treated in our hospital between January 1,2014 and December 31,2015 were selected, who completed 3 years of follow-up after discharge. The TIMI risk score was recorded of each patient to follow up on the endpoint events within 3 years.Results The incidence of endpoint events in patients with different risk stratification was compared. The incidence was 99.65% for the high score group, 35.35% for the middle score group, and 13.71% for the low score group, so the difference was statistically significant (P<0.05). The three-year mortality rate of patients with different risk stratification was compared: 19.96% for the high score group, 5.33% for the middle score group and 1.31% for the low score group. The difference was also of statistical significance (P<0.05).The AUC of the TIMI risk score was 0.7996, while 95%CI was 0.7962-0.8030.Conclusions The higher the TIMI risk score in AMI patients, the higher the incidence of endpoint events within 3 years of follow-up, the higher fatality rate and the worse long-term prognosis. TIMI risk scores can effectively help predict the prognosis in patients with AMI.
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Received: 29 January 2019
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[1] |
Littnerova S, Kala P, Jarkovsky J, et al. GRACE score among six risk scoring systems (CADILLAC, PAMI, TIMI, Dynamic TIMI, Zwolle)demonstrated the best predictive value for prediction of long-term mortality in patients with ST-elevation myocardial infarction[J]. PLoS One, 2015,10(4): e0123215.
|
[2] |
Worner F, Cequier A, Bardaji A, et al. Comments on the ESC guidelines for the management of acute myocardial in-farction in patients presenting with ST-segment elevation[J]. Rev Esp Cardiol (Engl Ed), 2013, 66(1):5-11.
|
[3] |
高晓津,杨进刚,吴 超,等. TIMI 风险评分与 GRACE 风险评分对中国 ST 段抬高型心肌梗死患者院内死亡率的预测价值[J].中国循环杂志,2018,33(6):529-534.
|
[4] |
Thygesen K, Alpert J S, Jaffe A S, et al. Third universal definition of myocardial infarction[J]. Circulation, 2012, 126(16): 2020-2035.
|
[5] |
Morrow D A, Antman E M, Charlesworth A, et al. TIMI risk score for ST-elevation myocardial infarction: a convenient, bedside, clinical score for risk assessment at presentation: an intravenous nPA for treatment of infarcting myocardium early II trial substudy[J]. Circulation, 2000,102(17): 2031-2037.
|
[6] |
周玲玲,吴 博,何 军,等.2010年—2016年某医院急性心肌梗死发病和死亡统计分析[J].中国病案,2018,19(2):59-62.
|
[7] |
王德征, 沈成凤, 张 颖, 等.天津市15年急性心肌梗死发病率变化趋势分析 [J] .中华心血管病杂志,2017,45(2): 154-159.
|
[8] |
高玉龙,陶 英,李志忠.心肌梗死溶栓试验危险评分对急性心肌梗死患者预后的评估价值[J].中国全科医学,2014,17(22):2599-2602.
|
[9] |
张立杰,王晓玲,宋巧凤,等.健康行为和因素评分对心脑血管事件及全因死亡的影响及研究[J].中国循证心血管医学杂志,2018, 10(6):675-677.
|
[10] |
Amin S T, Morrow D A, Braunwald E, et al. Dynamic TIMI risk score for STEMI[J]. J Am Heart Assoc, 2013, 2(1): e003269.
|
[11] |
De Luca G, Suryapranata H, Van Hof A W, et al. Prognostic assessment of patients with acute myocardial infarction treated with primary angioplasty: implications for early discharge[J]. Circulation, 2004, 109(22): 2737-2743.
|
[12] |
Halkin A, Singh M, Nikolsky E, et al. Prediction of mortality after primary percutaneous coronary intervention for acute myocardial infarction: the CADILLAC risk score[J]. J Am Coll Cardiol, 2005, 45(9): 1397-1405.
|
|
|
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