持续性非卧床腹膜透析对颈动脉中膜厚度的影响

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Abstract Objective To explore the influencing factors of carotid intima-media thickness in continuous ambulatory peritoneal dialysis patients.Methods The continuous ambulatory peritoneal dialysis(CAPD) patients were divided into the increased CIMT group(CIMT≥1.0 mm) and normal CIMT group (CIMT＜1.0 mm) based on their carotid color Doppler ultrasound results. The relationships between serum phosphorous, hs-CRP, IL-6 and the increased CIMT were analyzed in the two groups.Results The proportion of the increased CIMT in CAPD patients was 45.83%. The differences in age, numbers of diabetes mellitus patients, serum phosphorous, hs-CRP, IL-6 and TNF-α between the two groups were statistically significant (P<0.05). Multivariate logistic regression analysis showed that serum phosphorous (P=0.003, OR=1.113), hs-CRP (P=0.001, OR=1.148) and IL-6 (P=0.016, OR=1.056) were significant independent risk factors for the increased CIMT in CAPD patients.Conclusions The thickening of CIMT in CAPD patients is related to serum phosphorous, hs-CRP, IL-6 and other factors, which is an important risk factor for the occurrence of vascular calcification and cardiovascular complications in CAPD patients.

Key words： peritoneal dialysis carotid intima- media thickness influencing factor

Received: 08 August 2019

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	Articles by authors
	GAO De
	GAO Feng
	SHI Changqian
	HE Xiao

Cite this article:

GAO De,GAO Feng,SHI Changqian等. Influencing factors of carotid intima-media thickness in continuous ambulatory peritoneal dialysis patients[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(12): 1062-1064.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2019/V30/I12/1062

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