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Real-time ultrasound elastography in evaluating carotid atherosclerosis plaques |
CHEN Xulan1, WU Xiaowei1, CAI Wei2 |
1. Department of Ultrasonic; 2. Institute of Cardiovascular Disease,Characteristic medical Center of the Chinese People's Armed Police Force, Tianjin 300162, China |
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Abstract Objective To assess the stability of carotid atherosclerosis plaques by ultrasound elastography imaging in order to predict acute cerebral infarction. Methods Sixty in-patients with acute cerebral infarction were enrolled between January and September in 2016 (acute cerebral infarction group), while another 55 out-patients undergoing cervical vascular examination in the Affiliated Hospital of People's Armed Police Logistics University served as the control group. The baseline data of the two groups was collected as well, including BMI, disease history, blood pressure and results of biochemical tests. The carotid intima media thickness (IMT) and plaque echo features were observed using conventional 2D ultrasound methods. The associated elastic parameters (e.g. elastic score, elastic area ratio) were acquired from the plaques' elastic dynamic image information through real-time elastography. Statistical analysis was performed. Results IMT in the acute cerebral infarction group (1.71±0.20) was significantly higher than in the control group (1.34±0.27) (P<0.05). The low echo plaque elastic score and the mixed echo plaque elastic score were both significantly lower in the control group than in the acute cerebral infarction group(1.22±0.43 vs 1.73±0.78,P=0.033;2.95±0.51 vs 3.38±0.59,P=0.036, respectively). The low echo plaque elastic area ratio and mixed echo plaque elastic area ratio were both significantly lower in the acute cerebral infarction group than in the control group (1.15±0.09 vs 1.23±0.10,P=0.029;1.44±0.12 vs 1.55±0.09,P=0.010, respectively). Conclusions The stability of carotid artery plaques can be identified by ultrasound elastography imaging to predict acute cerebral infarction.
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Received: 10 July 2019
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