|
|
Clinical Study on Combined Application of Color Doppler Ultrasound, Molybdenum Target and MRI in Detection of Early Breast Cancer |
REN Hongchang, YANG Jianwu, LI Chenglin, ZHOU Yinghao, YANG Heming |
Strategic Support Force Medical Center, Beijing 100101, China |
|
|
Abstract Objective To study the combined detection value of color Doppler ultrasound, molybdenum target and MRI for early breast cancer. Methods From January 2018 to October 2019, 118 patients with suspected early breast cancer who had been detected by color Doppler ultrasound, molybdenum target and MRI before operation were retrospectively analyzed. In terms of sensitivity, specificity and accuracy, the postoperative pathological diagnosis was taken as the gold standard, and the differences of color Doppler ultrasound, molybdenum target, MRI and their combined detection were compared. Results Among 118 patients, breast cancer was suspected to be detected preoperatively: color Doppler ultrasound in 87 cases, molybdenum target in 88 cases, MRI in 92 cases, and 103 cases were detected by combination of the three. Preoperative detection of benign breast lesions: color Doppler ultrasound in 31 cases, molybdenum target in 33 cases, MRI26 in 26 cases, combined detection of the three in 15 cases; Postoperative pathology diagnosed 106 cases of breast cancer and 12 cases of benign breast lesions. The sensitivity of color Doppler ultrasound, molybdenum target, MRI and their combined detection are 79.25%, 80.19%, 84.91% and 97.17% respectively. The specificity was 75.00% for color Doppler ultrasound, 75.00% for molybdenum target, 83.33% for MRI, and 100.00% for combination of the three. The accuracy rates were 78.81% for color Doppler ultrasound, 79.66% for molybdenum target, 84.75% for MRI, and 97.46% for combination of the three. In terms of sensitivity, specificity and accuracy, the combined detection of color Doppler ultrasound, molybdenum target and MRI is higher than each single detection, with statistically significant difference (P<0.05). Conclusions Combined application of color Doppler ultrasound, molybdenum target and MRI to detect early breast cancer has greatly improved sensitivity, specificity and accuracy, and its clinical value is worthy of promotion.
|
Received: 14 September 2020
|
|
|
|
|
[1] |
Romagnolo A P, Romagnolo D F, Selmin O I. BRCA1 as target for breast cancer prevention and therapy[J]. Anticancer Agents Med Chem,2015,15(1):4-14.
|
[2] |
罗 义,魏成刚,李阳敏.核磁共振、乳腺钼靶、彩超对早期乳癌影像诊断的对比分析[J].川北医学院学报,2014,29(1):72-75.
|
[3] |
林 雅,章 杰,林 义,等.乳腺癌组织中 CC 类趋化因子5和重组人S100钙结合蛋白 A4表达与临床病理特征及预后的关系[J].中国基层医药,2017,24(6):828-833.
|
[4] |
Siegel R L, Miller K D, Jemal A. Cancer statistics, 2016[J]. CA Cancer J Clin, 2016,66(1):7-30.
|
[5] |
Zeng H, Zheng R, Guo Y, et al. Cancer survival in China, 2003-2005: a population-based study[J]. Int J Cancer,2015,136(8):1921-1930.
|
[6] |
Chen W, Zheng R, Zhang S, et al. Report of cancer incidence and mortality in China,2010[J]. Ann Transl Med,2014,2(7):61.
|
[7] |
Fan L, Strasser-Weippl K, Li J J, et al. Breast cancer in China[J]. Lancet Oncol, 2014,15(7):e279-e289.
|
[8] |
汪 勇.分析高频彩超在乳腺良恶性病变诊断中应用[J].影像研究与医学应用,2019,3(9):206-207.
|
[9] |
张婧姝,郑 慧.彩色多普勒超声诊断乳腺癌的价值[J].安徽医药,2018,22(8):1475-1477.
|
[10] |
中国抗癌协会乳腺癌专业委员会.中国抗癌协会乳腺癌诊治指南与规范(2019年版)[J].中国癌症杂志,2019,29(8):609-679.
|
[11] |
王思佳,吴金萍.彩色多普勒超声成像和乳腺X线摄影对早期乳腺癌诊断价值的对比[J].河北医学,2016,22(1):78-81.
|
[12] |
Keatmanee C, Chaumrattanakul U, Kotani K, et al. Initialization of active contours for segmentation of breast cancer via fusion of ultrasound, doppler, and elasticity images[J]. Ultrasonics,2019,94:438-453.
|
[13] |
Dellaportas D, Koureas A, Contis J, et al. Contrast-enhanced color doppler U1trasonnography for preoperative evaluation of sentinel lymph node in breast cancer patients[J]. Breast Care (Basel),2015,10(5):331-335.
|
[14] |
朱柯斌,袁 硕.介入超声在甲状腺疾病诊疗中的应用价值分析[J].中国保健营养,2018,28(29):309-310.
|
[15] |
罗凤莲,漆 赤,何莎莎,等.钼靶、超声联合MRI检查对早期乳腺癌诊断的价值[J].中国CT和MRI杂志,2016,14(5):65-67.
|
[16] |
胡晓坤.探讨乳腺钼靶摄片及彩色多普勒B超在早期乳腺癌诊断中的优势及价值[J].吉林医学,2013,34(11):2107-2108.
|
[17] |
任 红,于学林,崔进国.超声与X线钼靶在乳腺癌诊断中的应用[J].实用放射学杂志,2013,29(6):899-901.
|
[18] |
史春颖,李亭亭,于兰英,等.位相对比乳腺摄影和彩色多普勒超声成像对早期乳腺癌诊断价值的对比研究[J].哈尔滨医科大学学报,2014,17(5):416-418.
|
[19] |
李金莉.核磁共振、乳腺钼靶、彩超对早期乳癌影像诊断的对比分析[J].临床医药文献电子杂志,2017,4(57):11227-11228.
|
[20] |
陈 龙,任千里.数字化钼靶X线在乳腺良恶性病变诊断中的应用研究[J].河北医学,2018,24(4):644-647.
|
[21] |
史晓燕.乳腺超声、钼靶及超声联合钼靶诊断早期乳腺癌的临床研究价值回顾性分析[D].山西医科大学,2016:1-40.
|
[22] |
张传芸,陈国庆.乳腺钼靶与超声联合检查在早期乳腺癌筛查中的应用[J].实用临床医药杂志,2015,19(3):30-32.
|
[23] |
Gonzalez V, Sandelin K, Karlsson A, et al. Preoperative MRI of the breast (POMB) influences primary treatment in breast cancer: a prospective, randomized, multicenter study[J]. World J Surg,2014,38(7):1685-1693.
|
[24] |
Sutton E J, Dashevsky B Z, Oh J H, et al. Breast cancer molecular subtype classifier that incorporates MRI features[J]. J Magn Reson Imaging, 2016,44(1):122-129.
|
[25] |
Destounis S, Arieno A, Morgan R. Personal history of premenopausal breast cancer as a risk factor for referral to screening breast MRI[J]. Acad Radiol, 2016,23(3):353-357.
|
|
|
|