cN0期甲状腺乳头状癌中央区淋巴结转移的危险因素分析

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Abstract Objective To analyze the risk factors of central lymph node(CLN) metastasis in patients with cN0 stage papillary thyroid carcinoma(PTC).Methods: We retrospectively studied 570 patients with cN0 stage PTC who underwent bilateral CLN dissection in Peking Union Medical College Hospital from 2013 to 2015. CLN metastasis was identified by histopathology. Patients with different CLN metastasis statuses were compared according to clinical, sonographic and pathological parameters.Results The prevalence of CLN metastasis was 49.5% in cN0 patients with PTC. CLN metatasis was independent associated with Male(OR=1.787, 95% CI:1.066-2.997, P=0.028), <45 years old(OR=2.063, 95% CI:1.366-3.115, P=0.001), multifocal lesions (OR=1.764, 95% CI:1.134-2.743, P=0.012), tumor diameter(OR=1.844, 95% CI:1.201-2.831, P=0.005) >1 cm, microcalcification(OR=1.965, 95%,CI:1.296-2.979, P=0.001) and capsular invasion (OR=2.868, 95% CI:1.880-4.377, P=0.000) were independent risk factors.Conclusions The CLNM rates of PTC cN0 patients with the six factors (Male, <45 years old, multifocal lesions, tumor diameter>1 cm, microcalcification and capsular invasion) were relatively higher than those without. These findings may be useful for identifying patients at higher central lymph node metastasis risk, who may require more aggressive treatment or intensive follow-up management.

Key words： papillary thyroid carcinoma cN0 Lymph node metastasis ultrasound central Lymph node metastasis

Received: 01 December 2020

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	Articles by authors
	ZHANG Xuehe
	GAO Luying
	ZHAO Ruina
	HUANG Xuepei
	LIU Ruifeng
	SHI Xinlong
	XIA Yu

Cite this article:

ZHANG Xuehe,GAO Luying,ZHAO Ruina等. Prediction of central lymph node metastasis in cN0 stage papillary thyroid carcinoma[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2021, 32(5): 407-410.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2021/V32/I5/407

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