体外模拟预混法应用于老年危重患者血管活性药物管路更换的临床效果

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Abstract Objective To evaluate the clinical effect of the in vitro simulation premixed method during the maintenance of hemodynamic stability when multiple vasoactive drugs are replaced among elderly and critically ill patients. Methods Between June 2016 and October 2020, 98 elderly and critically ill patients in our hospital were randomly divided into the premixed group and control group, with 49 cases in each. In the control group, venous fluid and vasoactive drugs were correctly arranged and connected with the three-way connector, the old tube was removed after connecting the extension tube for exhaust, and the new tube was connected with the venous catheter. In the premixed group, the in vitro simulation premixed method was adopted, which involved connecting and running the micro pump to premix the drug for 3 minutes before replacing the tube. Blood pressure and heart rate were measured before tube replacement and 1 min, 3 min, 5 min and 10 min after replacement in the two groups. The fluctuations and recovery time of blood pressure, heart rate before and after replacement were recorded for three consecutive days. Results There were significant differences in systolic blood pressure at 3 min,5 min,10 min after replacement[(15.55±5.59)mmHg,(6.59±1.74)mmHg and(5.02±1.51)mmHg]in the premixed group versus[(47.02±6.36)mmHg,(25.51±5.60)mmHg and(10.69±4.10)mmHg]in the control group. There was no significant difference between the two groups at 1 min after replacement, but there was significant difference at 3 min, 5 min and 10 min after replacement. Conclusions The in vitro simulation premixed method, when used to replace the infusion tube for the elderly and critically ill patients treated with vasoactive drugs, can effectively reduce the fluctuations of blood pressure and heart rate, shorten the recovery time of blood pressure and heart rate after tube replacement, and maintain the stability of hemodynamics.

Key words： elderly critically ill patients vasoactive drugs replacement of infusion tubes micropumps

Received: 10 June 2021

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	Articles by authors
	GUO Yan
	SHI Haiyan
	MA Xiao
	WANG Lu
	MA Yawei

Cite this article:

GUO Yan,SHI Haiyan,MA Xiao等. Evaluation of an alternative medicinal administration method by mixing multiple vasoactive drugs in vitro among elderly and the critically ill patients[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(3): 215-218.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2022/V33/I3/215

[1]	王彬,于晓江,马翠华. 微量泵入去甲肾上腺素维持危重症患者循环稳定的应用[J]. 实用药物与临床, 2010,13(6): 464-465.
[2]	陈秀妹. 改良续泵方式对使用血管活性药物老年心脏术后患者循环系统的影响[J]. 医药前沿,2017,7(19):145-146.
[3]	倪晓燕. CCU 患者应用微量注射泵存在的问题与护理对策[J]. 医学信息,2015,28(15):98.
[4]	耿爱香.微量泵安全输注血管活性药物的研究进展[J].中国医疗器械信息,2020,26(16):17-19.
[5]	王倩,李亚男,郝楠. 双泵续泵并行法在体外循环术后持续输注血管活性药物中的应用效果[J]. 护士进修杂志,2017,32(8):747-749.
[6]	熊玉如.自动化智能微量泵对药物续泵更换用于心脏术后应用大剂量血管活性药物患者的临床效果[J].全科护理,2019,17(21):2571-2573.
[7]	柳青,李慧芳,刘丽凤,等. 盐酸地尔硫卓和硝酸甘油联合治疗不稳定型心绞痛的效果[J]. 武警医学, 2012, 23(8): 671-673.
[8]	张琼,刘锦华,李鹤琴,等.血管活性药物肾上腺素对重症感染性休克患者肾功能及血流动力学指标的影响[J].解放军预防医学杂志,2019,37(2):48-50.
[9]	薄其果,张红梅,栾云洋,等.微量注射泵末端输出压力变化对给药精度影响的实验研究[J].护理研究,2013,27(11):1048-1050.
[10]	原鑫鑫.微量泵泵入血管活性药物安全隐患与对策的研究进展[J].当代护士(中旬刊),2016,(11):9-10.
[11]	徐文红,高玲,冯锦茶,等.自动化智能微量泵在血管活性药物续泵更换中的应用[J].中华现代护理杂志,2017,23(34):4388-4390.
[12]	王蕾,关欣.血管活性药物续泵方法的现状与思考[J].中国实用护理杂志,2018,34(15):1125-1129.
[13]	郑丽红, 矫俊, 梁晓丽. 改良微量泵更换药物法在小儿先心病术后监护中的应用[J].护士进修杂志,2017,32(21): 2010-2011.
[14]	李晶,孙海玲.应用微量泵安全管理的研究进展[J].中华现代护理杂志,2009,15(31):3324-3326.
[15]	赵楠,陈献,哈玲梅,等. 心脏临时起搏器对颈内动脉支架置入术围术期并发症的影响[J]. 武警医学,2021,32(10):840-842.
[16]	唐志红,李思宇,陈瑶 . 重症医学科护士选择升压药物续泵方式的调查[J]. 中华现代护理杂志,2017,23(1):71-74.