婴幼儿呼吸道合胞病毒和人鼻病毒感染所致急性下呼吸道感染特征及预后分析

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Abstract Objective To investigate the clinical characteristics of acute lower respiratory tract infections caused by respiratory syncytial virus (RSV) and/or human rhinovirus (HRV) in infants. Methods Clinical data of 138 infantile patients with acute lower respiratory tract infection, who were admitted to Characteristic Medical Center of Chinese People's Armed Police Force from January 2012 to December 2017, were divided into three groups: simple RSV group (84 cases), simple HRV group(20 cases), and coinfection group of RSV and HRV(84 cases). Clinical characteristics of the three groups were compared, and associations between respiratory viral infections, recurrent wheeze and asthma at aged 6-8 were analyzed. Results The infants with simple RSV infection was the youngest [(5.64±2.16) months, the proportion of respiratory failure was the highest (25.00%), the demand for oxygen was the highest (25.00%),and the difference was statistically significant (P<0.05). At the last follow-up visit, the rates of recurrent wheezing in RSV infection group, HRV infection group and RSV and HRV coinfection group were 39.29%, 20.00% and 35.29% respectively, and the rates of asthma were 7.14%, 10.00% and 11.76% respectively, with no significant difference (P>0.05). In the simple RSV group, the proportion of recurrent wheezing during the age of 6~8 years with family history of asthma (87.50%) was higher than that those without family history (23.08%) and the difference was statistically significant (P<0.001). Conclusion Infants with simple RSV infection are characterized by a higher proportion of respiratory failure, and infants with a family history of asthma are more likely to suffer from recurrent wheeze at the age of 6-8 years.

Key words： respiratory syncytial virus human rhinovirus acute lower respiratory tract infection recurrent wheezing asthma

Received: 15 May 2022

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	LIANG Gaili
	WANG Yanhua
	WANG Xiaojian
	ZHANG Qing

Cite this article:

LIANG Gaili,WANG Yanhua,WANG Xiaojian等. Clinical characteristics and prognosis of acute lower respiratory tract infections caused by respiratory syncytial virus and rhinovirus infections in infants[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(10): 857-861.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2022/V33/I10/857

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