脾原发淋巴瘤的磁共振表现

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (1827 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To analyze the magnetic resonance (MR) imaging features of primary splenic lymphoma.Methods The clinical data and MR imaging features of patients with pathologically-proved primary splenic lymphoma were retrospectively analyzed from January 2010 to June 2019. The following MRI features of the lesions were analyzed: signal intensity, necrosis, hemorrhage, cystic change, pseudo-capsule, enhancement features and invasion of surrounding structures. Divided into two groups according to single or multiple lesions, the clinical data and MRI features of the lesions were compared.Results A total of 13 patients with primary splenic lymphoma were collected (8 cases were single and 5 cases were multiple with a total of 34 lesions). Fourteen lesions (41.2%) showed iso- and hyperintense and 20 lesions (5.82.2%) showed hypointense on T₂WI; 30 lesions (88.2%) showed iso- and hypointense and 4 lesions (11.8%) showed hyperintense on T₁WI; 15 lesions (44.1%) showed hyperintense on diffusion-weighted imaging (DWI), including 6 heterogeneous hyperintense lesions (40.0%) and 19 lesions (55.88%) showed iso- and hypointense; tumor necrosis occurred in 11 lesions (32.4%), hemorrhage occurred in 6 lesions (17.7%), and no lesions had cystic change; 20 lesions (58.8%) had pseudo-capsule, of which 11 lesions (55.0%) had incomplete pseudo-capsule. All the lesions on dynamic contrast-enhanced MRI showed mild enhancement in the arterial phase and gradually enhanced. One patient (7.7%) had invasion of the pancreas, and one patient (7.7%) had invasion of the splenic flexure of colon. The size of the lesion, T₂WI and DWI signal characteristics, and the presence or absence of pseudo-capsule were statistically different between the two groups (P＜0.05).Conclusions The single lesion of primary splenic lymphoma is larger in diameter, T₂WI and DWI show iso- and hyperintense, and pseudo-capsule is more common, while the multiple lesions show mostly hypointense on T₂WI and DWI. The lesions in the two groups mostly show iso- and hypointense on T₁WI, bleeding and necrosis can occur, and the dynamic contrast-enhanced scan shows mild progressive enhancement.

Key words： magnetic resonance imaging primary splenic lymphoma diffusion weighted imaging

Received: 08 October 2022

ZTFLH:

R733.2

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHANG Hongtao
	SHENG Fugeng
	ZHANG Zhaoxue
	GAO Shen
	CUI Mengqiu
	XU Wei
	YE Huiyi

Cite this article:

ZHANG Hongtao,SHENG Fugeng,ZHANG Zhaoxue等. Magnetic resonance imaging features of primary splenic lymphoma[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2023, 34(2): 115-118.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2023/V34/I2/115

[1]	祁佩红,李四保,郑红伟,等.脾脏原发性淋巴瘤的CT、PET/CT表现 [J].中华肝胆外科杂志,2016,22(8):566-567.
[2]	Ingle S B, Hinge Ingle C R. Primary splenic lymphoma: current diagnostic trends[J]. World J Clin Cases, 2016, 4(12): 385-389.
[3]	Dasgupta T, Coombes B, Brasfield R D. Primary malignant neoplasms of the spleen [J]. Surg Gynecol Obstet, 1965, 120: 947-960.
[4]	Dachman A H, Buck J L, Krishnan J, et al. Primary non-Hodgkin's splenic lymphoma [J]. Clin Radiol,1998, 53(2): 137-142.
[5]	Kehoe J, Straus D J. Primary lymphoma of the spleen. Clinical features and outcome after splenectomy [J]. Cancer, 1988, 62(7): 1433-1438.
[6]	Karunanithi S, Sharma P, Roy S G, et al. Use of 18F-FDG PET/CT imaging for evaluation of patients with primary splenic lymphoma [J]. Clin Nucl Med, 2014, 39(9):772-776.
[7]	Shimizu-Kohno K, Kimura Y, Kiyasu J, et al. Malignant lymphoma of the spleen in Japan: a clinicopathological analysis of 115 cases [J]. Pathol Int, 2012, 62(9):577-582.
[8]	Shimono J, Miyoshi H, Kiyasu J, et al. Clinicopathological analysis of primary splenic diffuse large B-cell lymphoma [J]. Br J Haematol, 2017, 178(5): 719-727.
[9]	Li M, Zhang L, Wu N, et al. Imaging findings of primary splenic lymphoma: a review of 17 cases in which diagnosis was made at splenectomy [J]. PLoS One, 2013, 8(11): e80264.
[10]	Rini J N, Leonidas J C, Tomas M B, et al. 18F-FDG PET versus CT for evaluating the spleen during initial staging of lymphoma [J]. J Nucl Med, 2003, 44(7):1072-1074.
[11]	张淑芬.64层螺旋CT诊断脾脏原发性肿瘤的临床分析(附35例报告)[J].医学影像学杂志,2014, 24(4):661-664.
[12]	马全美,辛军,侯阳. 脾脏多发性结节病变的影像鉴别诊断[J].实用放射学杂志, 2020, 36(12):1961-1964.