Abstract：Objective To investigate the effect of group B streptococcal infection on pregnancy outcome in late pregnancy.Methods The data of 1455 cases of pregnant women in our hospital were collected from 2017-11 to 2018-03.GBS test was performed at 35~37 weeks of pregnancy, it was divided into GBS positive group and GBS negative group according to whether that GBS infection occurred. The GBS positive group was divided into treatment group A (oral antibiotic 7 days at 35-37weeks,except for conventional treatment at birth or after premature rupture of membranes) and treatment group B (routine treatment at birth or after premature rupture of membranes) according to the different treatment methods.Pregnancy outcomes were compared between treatment groups A and B, GBS positive group and GBS negative group.Results (1)The positive rate of GBS was 7.9% (115/1455) in 1455 pregnant women;(2)The incidence rates of premature rupture of membranes, premature delivery, intrauterine infection, cesarean delivery, amniotic fluid turbidity, postpartum hemorrhage, pneumonia of newborn, and neonatal infections in the GBS positive group were statistically significantly higher than those in the GBS negative group (P<0.05); (3)There was no statistically significant difference between the treatment group A and the treatment group B in the all observation indicators.Conclusions GBS infection will easily result in premature rupture of membranes and other adverse pregnancy outcomes. In order to avoid overuse of antibiotics, prophylactic treatment for streptococcus B carriers should be carried out at the time of labor or premature rupture of membranes, so as to achieve satisfactory infection control effect.
高飞,王雅慧,张敏洁,赵霞,张雪. 妊娠晚期B族链球菌感染对妊娠结局的影响[J]. 武警医学, 2018, 29(12): 1141-1143.
GAO Fei, WANG Yahui, ZHANG Minjie, ZHAO Xia, and ZHANG Xue. Effect of group B streptococcal infection on pregnancy outcomes in late pregnancy. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(12): 1141-1143.
Teatero S, Ferrieri P, Martin I, et al. Serotype distribution, population structure, and antimicrobial resistance of group B streptococcus strains recovered from colonized pregnant women[J]. J Clin Microbiol, 2017, 55(2): 412-422.
[5]
Egle B, Arnoldas B, Rasa T, et al. Prevalence of maternal group B streptococcal colonisation in European countries[J]. Acta Obstet Gynecol Scand, 2008, 87(3): 260-271.
[6]
Park J S, Cho D H, Yang J H, et al. Usefulness of arapid real-time PCR assay in prenatal screening for group B streptococcus colonization [J]. Ann Lab Med, 2013, 33(1): 39-44.
[7]
Lu B, Li D, Cui Y, et al. Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China [J]. Clin Microbiol Infect, 2014, 20(6): 370-373.
2018, Vol. 29 
