Abstract： Objective To explore the effect of antibiotics on inflammatory markers of colorectal polyps after surgery by means of argon plasma coagulation and electrocoagulation.Methods In this prospective study, 58 cases of patients with colorectal polyps received the endoscopic treatment. These patients were randomly divided into the antibiotic group (28 cases) and the non-antibiotic group (30 cases). The levels of plasma endotoxin, procalcitonin and C-reactive protein were measured before endoscopic treatment and one day, three days after treatment.Results No hemorrhage or perforation occurred in any of the cases after postpolypectom . The abdominal pain and abdominal distension occurred in nine cases (15.5%) after postpolypectomy, but the symptoms disappeared in twelve to twenty-four hours. Low fever after polypectomy occurred in one case (3.6%) in the antibiotic group, and the interval between polypectomy and the occurrence of fever was eight hours. Fever occurred after polypectomy in four of the thirty cases (13.3%) in the non-antibiotic group, and the median interval was seven to fourteen hours. There was significant difference between the two groups in the incidence of fever (P<0.05). The difference in plasma levels of endotoxin, procalcitonin and C-reactive protein was not statistically significant one day and three days after endoscopic treatment compared with preoperative levels in the two groups.Conclusions Colorectal polypectomy using argon plasma coagulation techniques and electric coagulation is considered safe. The inflammatory markers after endoscopic treatment are basically normal. Antibiotics should be used with caution.
张兴光,谢立群,邓全军,赵建业,赵军艳,陈金梅,耿丽媛. 抗生素对结直肠息肉氩离子凝固术及电凝电切术后炎性指标的影响[J]. 武警医学, 2018, 29(7): 653-652.
ZHANG Xingguang, XIE Liqun, DENG Quanjun, ZHAO Jianye, ZHAO Junyan, CHEN Jinmei, and GENG Liyuan. Effects of antibiotics on inflammatory markers of colorectal polyps after surgery via argon plasma coagulation and electrocoagulation. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(7): 653-652.
Calderwood A H, Schroy P C, David A, et al. Boston Bowel Preparation Scale scores provide a standardized definition of “adequate” for describing bowel cleanliness [J]. Gastrointest Endosc, 2014, 80(2): 269-276.
[3]
Tan Tao, Qu Yawei, Shu Juan, et al. Diagnostic value of high-resolution micro-endoscopy for the classification of colon polyps [J]. World J Gastroenterol, 2016, 22(5): 1869-1876.
[4]
Paggi S, Radaelli F, Repici A, et al. Advances in the removal of diminutive colorectal polyps [J]. Expert Rev Gastroenterol Hepatol, 2015, 9(2): 237-244.
[5]
Anderloni A, Jovani M, Hassan C, et al. Advances, problems, and complications of polypectomy [J]. Clin Exp Gastroenterol,2014,7: 285-296.
[6]
Seung-Hoon L, Kyung-Jo K, Dong-Hoon Y, et al. Postpolypectomy fever, a rare adverse event of polypectomy: nested case-control study [J]. Clin Endosc, 2014, 47(3): 236-241.
[7]
Hyung Wook K. What is different between postpolypectomy fever and postpolypectomy coagulation syndrome? [J]. Clin Endosc, 2014,47(3): 205-206.
[8]
Cha J M, Lim K S, Lee S H, et al. Clinical outcomes and risk factors of post-polypectomy coagulation syndrome: a multicenter, retrospective, case-control study [J]. Endoscopy, 2013,45(3): 202-207.
2018, Vol. 29 
