Abstract：Objective To explore the incidence of insulin resistance and metabolic syndrome in obese children and the relationships between them.Methods Eighty-eight obese children admitted to our hospital between January 2015 and August 2016 were selected as the subjects of this study. OGTT test was carried out and the children’s insulin levels and serum triglycerides, high-density lipoprotein and low density lipoprotein were measured.Results In these 88 cases of obese children, the number of cases with normal indicators of OGTT was 45, accounting for 51.14% of the total. Among the cases with abnormal results, there were 9 cases of fasting blood glucose damage, accounting for 10.23%, 31 cases of impaired glucose tolerance that accounted for 35.23%, 3 cases diagnosed as type 2 diabetes mellitus that accounted for 3.41%, and 41 cases of normal blood lipids that accounted for 46.59%. Among cases of abnormal blood lipids, there were 10 cases of reduced high-density lipoprotein that accounted for 11.36% and 7 cases of increased triglycerides and low-density lipoprotein that accounted for 7.95%, and 8 cases of decreased high-density lipoprotein accompanied by increased low-density lipoprotein, accounting for 9.09%.There were 21 cases of increased triglycerides and decreased high-density lipoprotein coupled with increased low-density lipoprotein , accounting for 23.86%. Among the 61 cases diagnosed with insulin resistance, abnormal lipid metabolism occurred in 41 cases, carbohydrate metabolism abnormalities in 38 cases, and metabolic syndrome in 31 cases. There were significant differences (P<0.05) in the incidence of lipid metabolism, carbohydrate metabolism and metabolic syndrome between children with insulin resistance and those without.Conclusions The incidence of insulin resistance and metabolic abnormalities is relatively high among obese children,which deserves more attention.
钟勇, 刘莉. 肥胖儿童胰岛素抵抗及代谢综合征发病分析[J]. 武警医学, 2019, 30(12): 1044-1046.
ZHONG Yong, LIU Li. Incidence of insulin resistance and metabolic syndrome in obese children and their correlations. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(12): 1044-1046.
2019, Vol. 30 
