Abstract：Objective To observe the therapeutic effect of bronchoscopic sputum aspiration against diabetes mellitus complicated with stroke-associated pneumonia.Methods Eighty-six patients with diabetes mellitus complicated with stroke-associated pneumonia were selected from Fuxing Hospital between July 2017 and December 2018. Among these patients, 66 were treated with the sputum suction tube (routine group) and the rest with sputum suction aided by a bronchoscope (intervention group). The clinical efficacy, sputum culture positive rate, duration and intensity of antimicrobial use, length of hospital stay, cost and adverse reactions were observed and compared between the two groups in order to evaluate the effect of bronchoscopic sputum suction in diabetes mellitus with SAP.Results In the course of treatment, the intervention group was treated with bronchoscopic sputum suction once or twice a week in addition to basic treatment, and each patient was treated with bronchoscopy (1.6±0.6) times, at an average interval of (7.8±2.3) days. The total effective rate (100%) of the intervention group was higher than that of the conventional group (74.2%) (χ2=4.899, P=0.027). The positive rate of sputum culture (70.0%) of the intervention group was higher than that of the conventional group (27.3%) (χ2=11.993, P=0.001). Antibiotics were used for a shorter period of time in the intervention group (8.3±1.9 days) than in the conventional group (11.0±8.0 days) (Z=-2.715, P=0.007). The intensity of antibacterials was lower in the intervention group (10.2±3.2)ddd than in the control group (13.5±8.0) ddd (t=-3.309, P=0.002). The average length of hospital stay in the intervention group (11.7±2.5 days) was shorter than in the conventional group (14.0±11.0) days (Z=-2.421, P= 0.015). The average cost of hospitalization in the intervention group (15956.2±4472.6)yuan was lower than in the conventional group (19673.5±15041.5) yuan (Z=-2.474, P=0.013). There were no adverse reactions such as hemoptysis or serious arrhythmia in either group.Conclusions Bronchoscopic sputum aspiration for diabetes mellitus complicated with stroke-associated pneumonia has good clinical efficacy and high positive rate of sputum culture. It can reduce the duration and intensity of antibiotic use, shorten the hospital stay of patients, reduce hospitalization costs, and cause no serious adverse reactions.
2020, Vol. 31 
