Abstract:Objective To retrospectively analyze the clinical effect of radiofrequency ablation and open surgery in the treatment of children with osteoid osteoma of femur. Methods A total of 24 patients with osteoid osteoma of femur (confirmed by postoperative pathology) admitted to the Department of Orthopedics, Beijing Children's Hospital Affiliated to Capital Medical University from April 2010 to February 2023 were selected, including 11 patients (8 males and 3 females) in the radiofrequency ablation group and 13 patients (9 males and 4 females) in the open surgery group. Clinical data of the patients were collected, including age, gender, follow-up time, pain scores before, 3 days after and at the last follow-up, duration of operation, length of stay, amount of blood loss, and number of intraoperative CT scans. Imaging data included preoperative tumor diameter and recurrence at last follow-up. Treatment effect was compared. Results The amount of surgical bleeding in the radiofrequency ablation group and the open surgery group was (1.73±1.19) ml and (12.31±5.99) ml, and the length of hospitalization was (8.27±1.27) d and (12.23±1.88) d, respectively. The number of intraoperative CT scans was (1.64±0.81) and (0.31±0.48), respectively, and the VAS scores at 3 days after surgery were (1.73±0.65) and (3.62±0.87), respectively, with statistical significance (P<0.05). There was 1 case of mild heat injury in the radiofrequency ablation group and 1 case of postoperative recurrence in the open surgery group. Conclusions Compared with open surgery, radiofrequency ablation for osteoid osteoma of femur in children has the advantages of less bleeding, shorter hospital stay and earlier recovery of pain symptoms, which is worthy of promotion. However, attention should be paid to avoid the occurrence of heat injury.
范竟一, 孙保胜, 张学军, 郭东. 射频消融和开放手术治疗儿童股骨骨样骨瘤的临床效果[J]. 武警医学, 2023, 34(12): 1046-1049.
FAN Jingyi, SUN Baosheng, ZHANG Xuejun, GUO Dong. Clinical effect of radiofrequency ablation and open surgery for osteoid osteoma of femur in children. Med. J. Chin. Peop. Armed Poli. Forc., 2023, 34(12): 1046-1049.
Jaffe H L. “Osteoid-osteoma” a benign osteoblastic tumor composed of osteoid and a typical bone[J]. Arch surg, 1935, 31(5): 709-728.
[2]
Agashe M, Vaidya S, Dhamele J, et al. CT-guided percutaneous drilling of osteoid osteoma: a safe, minimally invasive and cost-effective method[J]. Indian J Orthop, 2020, 54(2): 194-199
[3]
Motamedi D, Learch T J, Ishimitsu D N, et al. Thermal ablation of osteoid osteoma: overview and step-by-step guide[J]. Radiographics, 2009, 29(7): 2127-2141.
[4]
Tepelenis K, Skandalakis G P, Papathanakos G, et al. Osteoid osteoma: an updated review of epidemiology, pathogenesis, clinical presentation, radiological features, and treatment option[J]. In Vivo, 2021, 35(4): 1929-1938.
[5]
Orth P, Kohn D. Diagnostics and treatment of osteoid osteoma[J]. Orthopade, 2017, 46(6): 510-521.
[6]
Rosenthal D, Callstrom M R. Critical review and state of the art in interventional oncology: benign and metastatic disease involving bone[J]. Radiology, 2012, 262(3): 765-780.
[7]
Tsoumakidou G, Thénint M A, Garnon J, et al. Percutaneous image-guided laser photocoagulation of spinal osteoid osteoma: a single-institution series[J]. Radiology, 2016, 278(3): 936-943.
[8]
Kransdorf M J, Stull M A, Gilkey F W, et al. Osteoid osteoma[J]. Radio Graphics, 1991, 11(4): 671-696.
[9]
Schulman L, Dorfman H D. Nerve fibers in osteoid osteoma[J]. J Bone Joint Surg Am, 1970, 52(7): 1351-1356.
[10]
Makley J T, Dunn M J. Prostaglandin synthesis by osteoid osteoma[J]. Lancet, 1982, 2(8288): 42-42.
[11]
O’Connell J X, Nanthakumar S S, Nielsen G P, et al. Osteoid osteoma: the uniquely innervated bone tumor[J]. Mod Pathol, 1998, 11(1): 175-180.
[12]
de Chadarevian J P, Katsetos C D, Pascasio J M, et al. Histological study of osteoid osteoma's blood supply[J]. Pediatr Dev Pathol, 2007, 10(5): 358-368.
[13]
Moberg E. The natural course of osteoid osteoma[J]. J Bone Joint Surg Am, 1951, 33-A(1):166-170.
[14]
Golding J S. The natural history of osteoid osteoma: with a report of twenty cases[J]. J Bone Joint Surg Br, 1954, 36-B(2): 218-29.
[15]
Boscainos P J, Cousins G R, Kulshreshtha R, et al. Osteoid osteoma[J]. Orthopedics, 2013, 36(10): 792-800.
[16]
Bottner F, Roedl R, Wortler K, et al. Cyclooxygenase-2 inhibitor for pain management in osteoid osteoma[J]. Clin Orthop Relat Res, 2001, 12(393): 258-263.
[17]
Carpintero-Benitez P, Aguirre M A, Serrano J A, et al. Effect of rofecoxib on pain caused by osteoid osteoma[J]. Orthopedics, 2004, 27(11): 1188-1191.
[18]
Bourgault C, Vervoort T, Szymanski C, et al. Percutaneous ct-guided radiofrequency thermocoagulation in the treatment of osteoid osteoma: a 87 patient series[J]. Orthop Traumatol Surg Res, 2014, 100 (3): 323-327.
[19]
Rimondi E, Mavrogenis A F, Rossi G, et al. Radiofrequency ablation for non-spinal osteoid osteomas in 557 patients[J]. Eur Radiol, 2012, 22 (1): 181-188.