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| Analysis of drug resisitance in 158 strains of Staphylococcus aureus |
| WU Chao1，YAN Kaili2，and DAI Yuanyuan3. |
1.Department of Clinical Laboratoy,Anhui Provincial Corps Hospital,Chinese People’s Armed Police Forces,Hefei 230041,China.
2. Anhui Provincial Center for Disease Control and Prevention, Hefei 230061,China.
3. Department of Clinical Laboratoy, Anhui Provincial Hospital, Hefei 230001,China |
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Abstract Objective To study the resistance of clinically-isolated Staphylococcus aureus to antimicrobial agents so as to facilitate the rational use of antibiotics. Methods The pathogenic bacteria were evaluated by VITEK32. Drug susceptibility test was carried out by K-B method. The results of 158 strains of Staphylococcus aureus were analysed by WHONET. Results 96 strains of MRSA were detected from 158 strains of Staphylococcus aureus ,which accounted for 60.76%. All the MRSA was resistant to penicillin and ampicillin but was sensitive to vancomycin. The resistance rate of MSSA to penicillin and ampicillin was 69.35% and 67.74%, respectively, and all the MSSA was sensitive to linezolid, quinupristin/dalfopristin and vancomycin. Conclusions Staphylococcus aureus is one of the main pathogens of clinical infection. Analysis of drug resistance of Staphylococcus aureus can guide the clinical use of antibiotics.
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Received: 08 March 2012
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| ［1］ |
刘静，刘红，韩忠学，等．烧伤患者血培养菌谱调查及耐药性分析［J］.武警医学，2010，21（10）：272-274.［2］孙玉坤，姚辉，于兰，等．我院感染病原菌的分布及其耐药性分析［J］．武警医学，2011，22（7）：195-198.［3］NearyM.MRSAinhospitals［J］.NursStand,2011,26(15-17):57.［4］李素梅.131株耐甲氧西林金黄色葡萄球菌的耐药性分析［J］.广东医学院学报,2007，25(4):439-440.［5］KohlenbergA,SchwabF,BehnkeM,etal.Correction:screeningandcontrolofmethicillin-resistantstaphylococcusaureusin186intensivecareunits:differentsituationsandindividualsolutions［J］.CritCare,2012,16(1):402-404.［6］刘晓霞，刘蓬蓬，孙运波.耐甲氧西林金黄色葡萄球菌感染的危险因素分析［J］.齐鲁医学杂志,2009,24(5):447-450.［7］HoTT,CadenaJ,ChildsLM,etal.Methicillin-resistantstaphylococcusaureusbacteraemiaandendocarditistreatedwithceftarolinesalvagetherapy［J］.JAntimicrobChemother,2012,6:1032-1037.
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| ［1］ |
刘静，刘红，韩忠学，等．烧伤患者血培养菌谱调查及耐药性分析［J］.武警医学，2010，21（10）：272-274.［2］孙玉坤，姚辉，于兰，等．我院感染病原菌的分布及其耐药性分析［J］．武警医学，2011，22（7）：195-198.［3］NearyM.MRSAinhospitals［J］.NursStand,2011,26(15-17):57.［4］李素梅.131株耐甲氧西林金黄色葡萄球菌的耐药性分析［J］.广东医学院学报,2007，25(4):439-440.［5］KohlenbergA,SchwabF,BehnkeM,etal.Correction:screeningandcontrolofmethicillin-resistantstaphylococcusaureusin186intensivecareunits:differentsituationsandindividualsolutions［J］.CritCare,2012,16(1):402-404.［6］刘晓霞，刘蓬蓬，孙运波.耐甲氧西林金黄色葡萄球菌感染的危险因素分析［J］.齐鲁医学杂志,2009,24(5):447-450.［7］HoTT,CadenaJ,ChildsLM,etal.Methicillin-resistantstaphylococcusaureusbacteraemiaandendocarditistreatedwithceftarolinesalvagetherapy［J］.JAntimicrobChemother,2012,6:1032-1037.
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